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521
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
Published 2017“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”
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522
Manipulating away the dizziness
Published 2016“…“The risk of getting BPPV increases as people get older and can be triggered by injury, infection, lack of sleep, prolonged immobility, stress, high blood pressure, low calcium levels and osteoporosis medications.”…”
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523
PDX1<sup>−</sup>/NKX6.1<sup>+</sup> progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells
Published 2020“…Also, the 3D-beta cells secreted C-peptide in response to increased glucose concentrations indicating their functionality.…”
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524
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …”