-
361
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
-
362
-
363
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
-
364
-
365
Tailoring motivational health messages for smoking cessation using an mHealth recommender system integrated with an electronic health record: a study protocol
Published 2018“…The usage of tailored health messages to support quitting has been proved to increase quitting success rates. Technology can provide convenient means to deliver tailored health messages. …”
-
366
-
367
-
368
A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
Published 2010“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
Get full text
Get full text
Get full text
article -
369
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017Get full text
Get full text
Get full text
article -
370
-
371
Detecting attacks in a cluster based QOS-OLSR protocol. (c2014)
Published 2014Get full text
Get full text
masterThesis -
372
-
373
A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter
Published 2020“…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …”
-
374
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. …”
Get full text
Get full text
Get full text
article -
375
Orofacial Clefts
Published 2021“…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …”
Get full text
Get full text
Get full text
masterThesis -
376
-
377
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …”
Get full text
Get full text
Get full text
article -
378
Quality of palliative care. Perspective of Lebanese patients with cancer
Published 2012“…The number of cancer patients in Lebanon is increasing, and patients are living longer due to early detection and enhanced methods of treatment. …”
Get full text
Get full text
Get full text
article -
379
Comparison between Nonlinear Analysis and ACI Simplified Effective Stiffness Analysis Methods for Reinforced Concrete Frames Under Lateral Load
Published 2023“…Conversely, employing the non-linear analysis method result in higher effective stiffness than simplified method by mean value of 1.36, 1.44 and 1.57 for frames with compressive strength 40,80 and 120mpa respectively. …”
Get full text
-
380
Adapted arithmetic optimization algorithm for multi-level thresholding image segmentation: a case study of chest x-ray images
Published 2023“…Particularly in recent years, there has been increased interest in determining the ideal thresholding for picture segmentation. …”
Get full text