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81
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Our results show that induction of SLFN11 expression can enhance DDA and DDR sensitivity in breast cancer cells and dCas9 systems may represent a novel approach to increase SLFN11 and achieve higher sensitivity to chemotherapeutic agents, improving outcome or decreasing required drug concentrations. SLFN11-targeting therapies might be explored pre-clinically to develop personalized approaches.…”
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82
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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83
Writing and publishing language studies in the Arab region [Khitabaat Journal]
Published 2024“…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …”
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Ozone and ozone/hydrogen peroxide treatment to remove gemfibrozil and ibuprofen from treated sewage effluent: Factors influencing bromate formation
Published 2020“…Bromate formation was decreased to 0.012 mg/L when the pH was increased to 9. …”
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86
Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
Published 2025“…In ACG patients, the pooled effect showed a percentage of IOP reduction (IOPR%) of 35.22% with a mean IOP reduction of −9.51 mmHg, <i>p</i>< 0.001 at 12 months, and an IOPR% of 27.47% with a mean reduction of −6.37 mmHg, <i>p</i> < 0.001 at 24 months. …”
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87
Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study
Published 2021“…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. …”
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88
Role of family in supporting children with mental disorders in Qatar
Published 2023“…There are certain behaviors of family members that can increase or decrease stress for the person. The results suggest that the family plays an essential role in supporting and promoting the lives of people with mental disorders and recommending effective ways to cope with them.…”
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The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…Here we present the effect of TTh on endocrine parameters in hypogonadal men at a 12-year follow-up. In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …”
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91
Examining time-to-transport decisions in Emergency Medical Services
Published 2024“…<h3>Background</h3><p dir="ltr">In modern healthcare systems, allocating resources and a patient-centred approach are crucial. While considerable efforts have been made to investigate emergency care and timing within the Emergency Medical Service (EMS)1,2,3, the subtleties surrounding time-to-transport decisions remain underexplored. …”
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92
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
Published 2023“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …”
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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97
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…However, removing <u>PANSS</u> scores notably decreased the model's diagnostic effectiveness. These results suggest that accessible peripheral laboratory parameters can serve as useful biomarkers for schizophrenia, potentially aiding in the early identification of TRS, enhancing personalized treatment strategies, and contributing to precision psychiatry. …”
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Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
Published 2020“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”
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Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
Published 2023“…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …”