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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”
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Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…”
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323
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”
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324
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…A CSTR nutrient-recovery line on digested <i>Scenedesmus</i> recovered 68 % N and 72 % P via struvite, reducing synthetic fertilizer ∼35 %; flue-gas CO<sub>2</sub> (12 % v/v) lifted biomass 22 % and reduced carbon-supplement cost 86 %. …”
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Influence of standardized patient body habitus on undergraduate student performance in an Objective Structured Clinical Examination
Published 2014“…Results: There was no difference in mean exam scores for students interacting with SPs with a normal BMI versus increased BMI (14.9 ± 2.2 versus 14.01 ± 2.2/20 respectively, p = 0.06). …”
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327
Exploring gender disparity in medicine: perceptions of female physicians in Lebanon
Published 2024“…In Lebanon, a nation celebrated for its diverse cultural landscape and increasing female representation in medical education, there has been a notable absence of studies exploring gender dynamics in the medical profession. …”
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328
Enhancing Thermal Comfort in Urban Communities with Urban Configurations and Green Coverage: A Case Study of Dubai Sustainable City
Published 2017“…Moreover, courtyard design impacts air distribution and air temperature, which is connected to predicted mean vote values, and green coverage percentage in the courtyard impacts microclimate variables, as it reduces air temperature by increasing relative humidity to a moderate level. …”
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329
Investigation of Provision of Services to Students of Determination in the Federal Higher Education Institute in the UAE
Published 2020“…In the analysis of quantitative data, t-test, was conducted to examine the differences between the mean score. Qualitative data from interviews and focus group was analyzed using thematic analysis. …”
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330
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…The global burden of overweight and obesity has increased by threefold since the 1970s, which led to increased incidences of cardiovascular disease and type 2 diabetes. …”
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331
Strategy Engineering as an Emergent Phenomenon for Successful Organisations
Published 2021“…The strategy engineering model consists of strategy resources and organisation development pillars wherein strategy engineering is a means to achieve effective strategic implementation and strategy success, thus satisfying and utilizing certain tools and techniques. …”
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332
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”
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Parental consanguinity and family history of coronary artery disease strongly predict early stenosis
Published 2010“…Results Family history of CAD and gender significantly increased the risk for young age at diagnosis of CAD (p < 0.001). …”
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334
Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus
Published 2017“…We sought to identify significant differences in overall/cardiovascular risk between hypertension with and without diabetes mellitus. Mean follow-up was 12.7 years; 14 050 all-cause deaths were reported. …”
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335
Shear behavior of green concrete beams reinforced with basalt FRP bars and stirrups
Published 2021“…In addition, the BFRP stirrups were effective in reducing the diagonal shear crack width and increasing the ultimate shear capacities of the tested beams. …”
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Emerging trends in direct air capture of CO<sub>2</sub>: a review of technology options targeting net-zero emissions
Published 2023“…In order to keep the global mean temperature at approximately 1.5 °C above the preindustrial era, the world needs increased deployment of negative emission technologies. …”
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Demographic characteristics and clinical and laboratory features of patients with Clostridiodes difficile infection: A retrospective study in Qatar
Published 2025“…ResultsOf the 595 patients, 308 (51.8%) were men with a mean age of 58 ± 19.9 years. The median duration of symptoms was 2 days, with an interquartile range values of 2-4 days. …”
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339
Crystallization properties of arsenic doped GST alloys
Published 2019“…Optical band gap (E<sub>opt</sub>) values of the as-deposited films show a clear increasing trend; 0.6 eV for GST to 0.76 eV for (GST)<sub>0.85</sub>As<sub>0.15</sub>. The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …”
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Inclusive Education-Perception of Parents of Students with Special Needs in Segregated Settings in Dubai
Published 2017“…Triangulation method was used to increase the validity and reliability of the study. …”
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