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1021
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…This absence of caspase activation was confirmed by a 72 hours cytotoxicity assay on Panc-1 cells, which revealed the failure of the pan-caspase inhibitor, Z-VAD, to reverse or decrease arginine depletion-triggered cell death. …"
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masterThesis -
1022
The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
منشور في 2023"…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…"
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1023
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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conferenceObject -
1024
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…The time required to develop bridging and subsequent clogging of the pore space that lead to permeability reduction decreases as the flow velocity increases. The size of the fine particles has a significant impact on permeability reduction where the reduction in permeability increases as the size of particles increases. …"
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1025
Inappropriate Medication Use in Elderly Lebanese Outpatients
منشور في 2006"…With increasing availability of newer and more appropriate medications, use of potentially inappropriate drugs may decrease. Pharmacists have a major role to play in counselling patients about the importance of appropriate drug use.…"
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article -
1026
Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
منشور في 2022"…Furthermore, CIP2A gene expression revealed that IM and (HU + IM) had the same therapeutic effect and were more successful in CML patients than HU alone. …"
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1027
Investigation of positive education implementation and its impact on students' wellbeing and academic self-efficacy in K-12 private schools in Dubai
منشور في 2022"…Guided by theories and perspectives of world culture theory, institutional theory, Seligman’s PERMA model, Ryff’s six-factor model of psychological wellbeing, Diener’s tripartite model of subjective wellbeing, Brofenbrenner eco-biological theory, social constructionism theory, self determination theory and social-cognitive learning theory. A convergent parallel mixed method research design was used in the study. …"
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1028
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
منشور في 2019"…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m<sup>2</sup> 21 days postoperatively. …"
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1029
An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
منشور في 2022"…This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. Given the high number of British as well as other non-Arabic schools in Dubai, this is a significant issue as many Arabic-speaking students are failing to achieve proficiency in their native language. …"
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1030
Business Continuity Management Maturity Model for Banks in UAE
منشور في 2008"…Although the awareness that something should be done to assure business continuity is present in many organizations, they often do not know how to implement BCM processes properly and integrate it through their entire set-up (end-to-end). According to a BCM survey conducted by KPMG (2006), same is the case with organizations in UAE, where only 20% of the organizations have an integrated organization-wide BCM. …"
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1031
Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming
منشور في 2024"…In addition, the presence of noble metals at the Ni surface afforded a high density of adsorbed oxygen species, which enhanced coke gasification and consequently decreased the extent of deactivation of the catalysts by coke formation. …"
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1032
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
منشور في 2018"…Furthermore, the role of Internal Audit is highlighted as the main procedure impacting the quality and reliability of risk management processes. The study adopts a quantitative methodology and employs a research philosophy of positivism in order to evaluate the collected data objectively and obtain results that create a visual representation of the identified research problem. …"
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1033
Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"
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1034
Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India?
منشور في 2025"…Similarly, Chloramphenicol sales decreased by 0.6% in the first month, whereas sales increased by a trend of 0.4% per month (IRR 1.004, 95%CI 0.991–1.017) post-intervention. …"
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1035
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1036
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …"
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1037
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
منشور في 2025"…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …"
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1038
Evidence-based safety education and training for traffic injury prevention
منشور في 2015"…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Journal of Local and Global Health Science, title discontinued as of (2017)<br>License: <a href="https://creativecommons.org/licenses/by/4.0/deed.en" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.5339/jlghs.2015.itma.89" target="_blank">https://dx.doi.org/10.5339/jlghs.2015.itma.89</a></p>…"
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1039
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
منشور في 2023"…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …"
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1040
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
منشور في 2023"…For the two-region model, dispersion coefficients were well defined and remained unchanged from the convective–diffusion equation for potassium ions but decreased for bromide ions. Retardation factors for bromide ions were approximately the same, but those for potassium ions, though > 1, were poorly defined. …"