Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies by Sabah Nisar (12561961)

“…Compared to the linear RNA, circRNAs are produced differentially by backsplicing exons or lariat introns from a pre-messenger RNA (mRNA) forming a covalently closed loop structure missing 3′ poly-(A) tail or 5′ cap, rendering them immune to exonuclease-mediated degradation. …”

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity by Vijay Gupta (209146)

“…In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …”

Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis by Salaheddin, Amira Talaat

“…Background: Pharmacists play a crucial role in healthcare systems worldwide. …”
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NLRP7 inter-domain interactions by El Maarri, Osman

“…We found that with the two clinically severe missense mutations, L398R and R693W, the normal molecule to molecule interaction was apparently affected thus decreasing their oligomerization potential while aggresome formation was increased; these changes could disturb the normal downstream functions of NLRP7 and therefore be a possible molecular effect underlying their pathophysiological impact.…”
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Prediction of critical total drawdown in sand production from gas wells: Machine learning approach by Fahd Saeed Alakbari (10701871)

“…<p></p><div> <p>Sand production is a critical issue in petroleum wells. The critical total drawdown (CTD) is an essential indicator of the onset of sand production. …”

Two-stage optimisation for malachite green removal using activated date pits by M. Hijab (14152095)

“…<p>Water pollution, from industry and agriculture, is a major threat to water security in the light of decreasing global potable water resources. …”

Crunching the numbers of food poisoning in Qatar by Nature Research (16552612)

“…<p>Salmonellosis is a common type of food poisoning caused by <i>Salmonella</i> bacteria. …”

Life cycle assessment and sustainability enhancement of closed-loop carbon dioxide enhanced oil recovery: Field-scale evaluation in Qatar’s Dukhan Reservoir by Razan Sawaly (19170910)

“…Global warming potential (GWP100) decreased from 2.00 × 10¹⁰ kg CO₂-eq in Year 1 to 1.20 × 10⁹ kg CO₂-eq in Year 21, with a 16% reduction observed in Year 1 under the fuel gas recovery scenario. …”

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice by Ann Van der Jeugd (18629695)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Scientific Reports<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-018-24741-0" target="_blank">https://dx.doi.org/10.1038/s41598-018-24741-0</a></p>…”

3D Printing Technology Utilizing Available Construction Materials in the UAE by Ahmed, Sara Khaled

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Polyaniline Based Composite Membranes for PEM Fuel Cells: Experiments and Factorial Design by Eisa, Ahmed

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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

“…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
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Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM by Ahmed Elrahmani (17128837)

“…The time required to develop bridging and subsequent clogging of the pore space that lead to permeability reduction decreases as the flow velocity increases. The size of the fine particles has a significant impact on permeability reduction where the reduction in permeability increases as the size of particles increases. …”

Biomarkers show promise for treatment of heart valve disease by Nature Research (16552612)

“…For example, previous studies have shown that replacement valves originating from animal tissue (bioprostheses) become calcified in patients with increased 1 levels of a type of low-density lipoprotein particles. The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …”

P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis by Milane, Aline

“…As such, efflux pumps are a major obstacle to drug brain distribution. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with little therapeutics available: riluzole is the only drug approved in its treatment. …”
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Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma by Abdalla, Eddie

“…The presence of hepatitis did not significantly affect the survival rate, but hepatic fibrosis and vascular invasion predicted a decreased survival rate. The prognosis after resection of HCC is influenced by tumor factors and liver disease, but not by HBV or HCV infection. …”
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Which firms export? An empirical analysis for the manufacturing sector in the MENA region by Fakih, Ali

“…Design/methodology/approach – This paper examines the factors influencing the export behaviour of manufacturing firms located in the MENA region through a probit model for export decision and through a fractional logit model for export intensity. …”
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Combinatory effect of diet and exercise on brain derived neurotrophic factor expression, cognitive function and behavioral phenotypes of psychiatric disorders. (c2017) by Abou Haidar, Edwina T.

“…We have also identified the branched chain amino acid leucine to be a crucial amino acid involved in BDNF induction. …”
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Functional fatigue of Ni50.3Ti25Hf24.7 - Heterogeneities and evolution of local transformation strains by Abuzaid, Wael

“…No homogenization of the transformation strain field was observed as a result of either stress increase or thermal cycling. …”
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Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines by Vahideh Akbari (18768001)

“…Halloysite nanotubes (HNTs) are unique 1D natural nanofillers with a hollow tubular shape and high aspect ratio. To tackle poor dispersion of the pristine halloysite (P-HNT) in the epoxy matrix, alkali surface-treated HNT (A-HNT) and epoxy silane functionalized HNT (F-HNT) were developed and cured with epoxy resin. …”