Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles حسب Elkhodiry, Mohamed A.

"…Results show an 80% increase in the accumulation of the antineoplastic agent in the FR+ cell line, when compared to the FR- cell line, thus providing evidence that the efficacy of Pluronic micelles, as drug delivery vehicles, can be enhanced via folic acid targeting.…"
احصل على النص الكامل

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

"…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Managing Endothelial Dysfunction in COVID-19 حسب Matli, Kamal

"…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention حسب Almonzer Al-Qiami (22393303)

"…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …"

Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Kinetic studies showed superior correlation with the pseudo-second-order model (R² > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"

Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials حسب Huzaifa Ahmad Cheema (16328980)

"…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …"

The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) حسب Zgheib, Perla Z.

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …"
احصل على النص الكامل
احصل على النص الكامل

Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge حسب ALMUTAWA, MUBARAK

"…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …"
احصل على النص الكامل

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"

Novel polysulfone ultrafiltration membranes incorporating polydopamine functionalized graphene oxide with enhanced flux and fouling resistance حسب Abedalkader Alkhouzaam (15842647)

"…The functionalization was confirmed using FTIR-UATR, Raman spectra, XPS, and SEM. Pristine PSF, PSF/GO, and PSF/rGO-PDA MMMs were then prepared using the phase inversion technique and analysed using FTIR, SEM, AFM, and contact angle (CA). …"

Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort حسب Ashraf T. Hantouly (14150319)

"…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…"

Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules حسب Bechnak, Linda

"…The cytotoxicity of curcumin and colloidal nanocapsules was assessed using human derived immortalized cell lines (A549 and A375 cells) in the presence and absence of light irradiation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …"

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition حسب Bouclaous, Carmel

"…All groups showed a decrease in relative intestinal absorption with time. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... حسب Kazandjian, Chant

"…Males demonstrated a significant decrease in anxiety scores compared to females. Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Glycemic Index of commonly consumed Lebanese mixed meals and desserts حسب Daher, C. F.

"…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes حسب Hammodat, Amina Rayan

احصل على النص الكامل

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells حسب Shilpa Kuttikrishnan (3520079)

"…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …"

Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells حسب Manale Karam (3619412)

"…Disruption of cell adhesion induced the subsequent differentiation of the highly expanded RA-derived EB-forming cells into a pure population of multipotent MSCs (up to 1542-fold increase in comparison to RA-untreated counterparts). …"