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441
Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans
منشور في 2024"…More recently, mutations in the tryptophanyl-tRNA synthetase 1 (WARS1) have been linked to various human diseases, from intellectual disability to various types of cancer. …"
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442
Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
منشور في 2019"…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …"
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443
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"
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444
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445
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446
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447
Implementation of corporate governance rules and procedures in lebanese firms
منشور في 2014"…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …"
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article -
448
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449
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450
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451
An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
منشور في 2022"…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …"
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masterThesis -
452
Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics
منشور في 2024"…Decadal variability is evident in element concentrations, which are linked to the urbanisation of the capital city in the State of Qatar. …"
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453
Collaborative hierarchical caching and transcoding in edge network with CE-D2D communication
منشور في 2020"…However, the high load in peak hours consumes the limited available bandwidth of existing cellular and backhaul links leading to low network performance. Hence, an elastic system model is required to maintain the high Quality of Experience (QoE) as the resource demands increase. …"
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454
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…InterpretationOver the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. …"
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article -
455
Collaborative Caching for D2D Content Sharing in 5G
منشور في 2021احصل على النص الكامل
doctoralThesis -
456
Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development
منشور في 2024"…We found that female mice exposed to PFOS alone showed an increase in weight, while HFD expectedly increased body weight. …"
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457
The Effects of Social Determinants of Health on Cardiovascular Outcomes in Lebanese with Type 2 Diabetes
منشور في 2020"…Background: Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases in Lebanon and is known to increase the risks of cardio-metabolic events. Diabetes self-management is essential for glycemic control and prevention of cardiovascular complications. …"
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masterThesis -
458
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…Interpretation Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. …"
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459
Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts ROLE IN SUPPRESSION OF c/EBP/NF-κB-MEDIATED MEKK...
منشور في 2006"…Cyclooxygenase-2 (COX-2) overexpression has been linked to cell survival, transformation, and hyperproliferation. …"
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article -
460
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
منشور في 2019"…Proteins susceptible to MG modification were enriched in protein folding, protein synthesis, serine/threonine kinase signalling, glycolysis and gluconeogenesis. MG was increased in high glucose by increased flux of MG formation linked to increased glucose metabolism mediated by proteolytic stabilisation and increase of hexokinase-2 (HK-2); later potentiated by proteolytic down regulation of glyoxalase 1 (Glo1) - the major enzyme of MG metabolism. …"