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381
P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…In the present study, we used a transgenic mouse model of ALS (G86R mSOD1 mice) to test this hypothesis. Expression and functionality of P-glycoprotein (ABCB1, P-gp) and Breast Cancer Resistance Protein (ABCG2, BCRP), two major efflux pumps, were studied. …”
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382
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …”
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masterThesis -
383
In-Vehicle Performance Validation of the Semi-Active Hybrid Energy Storage System
Published 2015“…The UCs supply the dynamic component of the load current which decreases the battery size, limits the battery peak current, and extends its life. …”
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384
Achieving a systematic service integration program for children with challenging behaviors in school setting in Lebanon. (c2015)
Published 2016“…However, there are limitations of this study, which need to be taken in consideration for further studies.…”
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masterThesis -
385
Seroprevalence of camel brucellosis in Qatar
Published 2022“…Only samples that tested positive by both tests were considered seropositive for brucellosis. …”
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386
Orofacial Clefts
Published 2021“…Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …”
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masterThesis -
387
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…The cytotoxic effect of fractions (10, 25, 50 and 100 μg/mL) was tested on human epidermal keratinocytes (non-tumorigenic HaCaT cells and tumorigenic HaCaT-ras variants) using WST a ssay. …”
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388
Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
Published 2022“…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”
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389
10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
Published 2020“…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …”
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390
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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391
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …”
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392
COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health
Published 2018“…Lebanon has the highest per-capita concentration of refugees worldwide. There is an urgent need to offer psychosocial interventions to vulnerable groups such as Syrian refugee adolescents. …”
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393
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394
Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs
Published 2021“…Specifically, precise pharmacological mechanisms and side effects need to be elucidated in human models before clinical benefits can be achieved.…”
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395
Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
Published 2024“…Such products need to be manufactured more often if companies want to survive in the Middle East as consumers will not settle for anything less. …”
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396
Post-materialistic values and entrepreneurial intention– the case of Saudi Arabia
Published 2018“…It also responds to the need to understand the difference in the levels of entrepreneurial activity across countries.…”
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397
Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…The same doses were used to test for anti-inflammatory activity against edema induced in hind paw by carrageenan. …”
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398
Breathing regulation and blood gas homeostasis after near complete lesions of the retrotrapezoid nucleus in adult rats
Published 2018“…CO2 detection, neuronal modulation) to the central respiratory chemoreflex (CRC). Here we test how important the RTN is to PCO2 homeostasis and breathing during sleep or wake. …”
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399
Prediction of critical total drawdown in sand production from gas wells: Machine learning approach
Published 2023“…The RSM correlation decreased the average absolute percent relative error (AAPRE) by 12.7% compared to all published correlations' AAPRE of 22.6%–30.4%. …”
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400
Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications
Published 2024“…The findings demonstrated that adding Mg influenced PCL’s mechanical and thermal properties. The mechanical test results showed that the tensile strength of 15% Mg composite filaments improved by around 10% compared to the neat PCL filaments. …”