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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
Published 2025“…Moreover, the overactivity of glycogen synthase kinase-3 beta (GSK-3β) also triggers taurine protein pathology. …”
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The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20...
Published 2020“…Findings In 2017, there were 6·8 million (95% UI 6·4–7·3) cases of IBD globally. The age-standardised prevalence rate increased from 79·5 (75·9–83·5) per 100 000 population in 1990 to 84·3 (79·2–89·9) per 100 000 population in 2017. …”
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A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
Published 2023“…The collective’s role in fostering social support was evident through decreased fearful reactions. Many lost trust in the judicial system and favored emigration over standing for justice. …”
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Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
Published 1991“…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …”
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1205
Bulk passivation of perovskite films utilizing halide anion ionic liquids
Published 2023“…These values show that the presence of the IL with chloride anion greatly improves the average lifetime of the charge carrier by around 250%, while IL with iodide anion decreased the lifetime by 32% as compared with the pristine perovskite sample. …”
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1206
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
Published 2023“…Additionally, IL-35 or THYO decreased TNF-α, NF-κB, IL-10, IL-6 and IFN-γ in contrast to the PAR control group. …”
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Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
Published 2003“…The present study was designed to verify if human (h) Angiotensin II (Ang II) type-1 receptor (hAT1R) undergoes internalization, nuclear translocation, and de novo synthesis in primary culture of human aortic vascular smooth muscle cells (hVSMCs) and if overexpression of this receptor modulates sustained free cytosolic ([Ca]c) and nuclear ([Ca]n) calcium. 3-dimensional (3-D) confocal microscopy was used to monitor free intracellular Ca2+ and hAT1R-green fluorescence protein (GFP) fusion protein in cultured hVSMCs. …”
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Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. …”
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Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust
Published 2020“…Atmospheric dust in Qatar is depleted in Al and enriched in calcium (Ca), in the form of calcium carbonate (CaCO<sub>3</sub>), relative to the global average Upper Continental Crust (UCC). …”
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1213
Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature
Published 2022“…Decidual vasculopathy (3.2%), infarction (3.2%), chronic histiocytic intervillositis (6.0%), thrombi vasculopathy (5.1%) were also observed in most of the MVM and FVM reported cases. …”
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1214
Zirconium Phosphate/Ionic Liquid Proton Conductors for High Temperature Fuel Cell Applications
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1215
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1216
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…The lowest number of functional groups occurred in the early ages (2–3 years old), and some groups either increased or decreased their frequency and abundance along the years. …”
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Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
Published 2023“…When the fluid is added with nanoparticles, like, Al2O3 and copper oxide (CuO) with different volumetric fractions (φ) of 0%, 0.5%, 1%, 1.5%, and 2%, the performance of the microchannel rises with rising the Reynolds number but conversely when the fluid is used in pure form the performance decreases with the rising value of Reynolds number. …”
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Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete
Published 2020“…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …”
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Hardware Trojan Mitigation Technique in Network-on-Chip (NoC)
Published 2023“…Compared to the runtime HT mitigation method, the proposed scheme also decreases the average latency for the hardware Trojan inserted in the flit’s header, tail, and destination field up to 14.7%, 8%, and 3%, respectively.…”
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Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…On average, it increases its diameter by 0.23 mm and decreases its length by 2.88 mm within 6 months of initial deployment. …”
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