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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms
منشور في 2008"…Conversely, treatment with GW9662 decreased TG mass and impaired adiponectin oligomer assembly but did not decrease total adiponectin mass. …"
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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays
منشور في 2016"…However, comparison of students' performance on lexical errors at the immediate post-test revealed that the self-feedback group significantly decreased this error percentage compared to the peer feedback group. …"
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Utilization of the Transparent Peer Review Policy to Train Graduate Pharmacy Students on Scientific Critique
منشور في 2024"…ResultsEleven students submitted reflections on their learning experiences through this public-facing peer review process. The analysis revealed that TPRP increased the students’ awareness of the peer review process and fundamental principles of scientific critique. …"
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Utilization of the Transparent Peer Review Policy to Train Graduate Pharmacy Students on Scientific Critique
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">Eleven students submitted reflections on their<u> learning experiences </u>through this public-facing peer review process. The analysis revealed that TPRP increased the students’ awareness of the peer review process and fundamental principles of scientific critique. …"
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Increased runoff through reduced infiltration in Saudi Arabia
منشور في 1979احصل على النص الكامل
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Rethinking (un)blinding in biomedical proposal peer review: A multi-stakeholder qualitative study
منشور في 2025"…These shortcomings highlight the need for greater openness in peer review and increased transparency in fund allocation processes.…"
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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
منشور في 2009"…Total cAMP hydrolytic activity as well as PDE3 and PDE4 activities were reduced in hypertrophied myocytes, because of a reduction of PDE3A, PDE4A, and PDE4B, whereas PDE4D was unchanged. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
منشور في 2023"…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …"
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Integration of Wind Catchers in Modern Residential Buildings in the UAE as a Means of Providing Thermal Comfort
منشور في 2014"…This research is an evaluation of the effectiveness of wind catchers as means of providing thermal comfort for modern residential buildings in the hot arid climates in the UAE. …"
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Kinetic studies showed superior correlation with the pseudo-second-order model (R<sup>2</sup> > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"
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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
منشور في 2018"…Treating differentiated adipocytes with PBA did not alter their differentiation status, but decreased the leptin to adiponectin ratio. Conclusion: this study showed that PBA enhances adipocyte glucose uptake potentially through its effect on glucose transporter expression and/or trafficking via the PI3K signaling pathway; suggesting PBA as a possible candidate for the ancillary management of diabetes.…"
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