Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). …”

Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making by Almutairi, Adel F.

“…The preferred duration for participation was 1–3 days (n = 268, 57%). Participants revealed their preferences of clinical trial studies were in favor: (a) vaccines (n = 209, 44.5%); (b) treatment drugs (n = 232, 49.4%); and (c) medical devices (n = 310, 66.0%). …”
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Diffusion tensor imaging with tractography in surgical resection of brainstem cavernous malformations: a systematic review and meta-analysis by Mohammed Maan Al-Salihi (13105835)

“…The utilization of preoperative diffusion tensor imaging significantly increased the proportion of improved patients and decreased the proportion of worsened patients. However, further controlled research is needed to draw a definite conclusion about the usefulness of its role.…”

Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants by Snigdhendubala Pradhan (9872262)

“…Two biochar application rates improved soil quality by increasing soil porosity from 49.3 to ≥ 53.4%, more than doubling cation exchange capacity to ≥ 21.1 cmolc.kg−1, providing a small reduction in bulk density of approximately 10% and decreasing electrical conductivity of the extract by at least 40% in comparison to control condition. …”

Coalition game theoretic P2P trading in a distribution network integrity-ensured local energy market by M., Imran Azim

“…This paper presents a peer-to-peer (P2P) trading-enabled local energy market (LEM) mechanism and analyses it in the Australian market context to verify its feasibility. …”
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Achieving a systematic service integration program for children with challenging behaviors in school setting in Lebanon. (c2015) by Mahmoud, Hadeel

“…This study aims at implementing a social skills based program/intervention on a child with behavioral problems. …”
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A Risk-Based Multi-Objective Modeling Approach to the Preventive Maintenance Process of Roof Waterproofing System at Airports by Shehab, Bahaa

“…The purpose of this study is to: (a) determine current waterproofing systems and components of concrete roofs at airports, (b) explore frequently used techniques to design optimal preventive maintenance policies, and (c) derive an optimal preventive multi-objective risk-based maintenance strategy via simulation that can diminish failure costs, thereby decreasing the system’s overall maintenance costs. …”
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A Risk-Based Multi-Objective Modeling Approach to the Preventive Maintenance Process of Roof Waterproofing System at Airports by Shehab, Bahaa

“…The purpose of this study is to: (a) determine current waterproofing systems and components of concrete roofs at airports, (b) explore frequently used techniques to design optimal preventive maintenance policies, and (c) derive an optimal preventive multi-objective risk-based maintenance strategy via simulation that can diminish failure costs, thereby decreasing the system’s overall maintenance costs. …”
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Determining the influencing factors in the residential rooftop solar photovoltaic systems adoption: Evidence from a survey in Qatar by Omar F. Alrawi (19418938)

“…<p>Renewable energy sources have developed rapidly, decreased in cost, and proven to have the potential to limit global warming. …”

Energy saving potential analysis applying factory scale energy audit – A case study of food production by Derar Al Momani (17831981)

“…It has been established that optimizing the factory’s energy use and the boiler systems' performance with regards to diesel consumption can withstand an expected monthly financial savings of 14205.85 Jordanian Dinar (JD). This has allowed a reduction in energy use of up to 18%. The CO₂ harmful emissions were also decreased. …”

Exploring the influence of salesperson lone wolf tendencies on customer value co-creation: a social exchange perspective by Itani, Omar S.

“…The study offers a clearer understanding of how LWTs impact sales and behavioral performance. …”
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A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering by Alessandro Ferrarini (3951098)

“…To this purpose, we first used multilabel algorithms in order to convert the task of explaining a large assemblage of plant communities into a classification framework able to capture with high cross-validated accuracy the pattern of species distributions under a composite set of biotic and abiotic factors. …”

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort by Mohamed Adil Shah Khoodoruth (14589828)

“…The NTRS group also showed higher HbA1c levels. Variations in inflammatory markers were noted, with the NTRS group exhibiting a higher platelet/lymphocyte ratio (PLR). …”

Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish by Fatiha M. Benslimane (6695087)

“…It enables practical real time visualization in a non-invasive manner, making the modality especially useful to image dynamic cardiac structures. …”

The Role of Cdc42 and the Cross-talk with RhoA/RhoC during Invadopodia Formation and Invasion in Glioblastoma Multiforme by Maalouf, Hiba

“…To better understand the signaling mechanism underlying Cdc42 positive regulation of invadopodia, we examined the effect of Cdc42 knockdown on the activation of RhoA. We found that Cdc42 depletion decreased RhoA activation which suggests that Cdc42 might be operating upstream of RhoA and regulating invadopodia formation through RhoA. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis by Charbel Abi Khalil (14150028)

“…Additionally, self-expandable valves were associated with a higher decrease in gradient than balloon ones (beta = 0.38; 95% CI [0.12–0.64]). …”

Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data by Squalli, Jay

“…It is estimated that a 10% increase in the share of renewable energy could decrease CH4 emissions by about 0.26%. …”
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A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats by Firas Feki (17545638)

“…Both extracts were administered to different rat groups via gavage (0.6 g/kg b.w.) before PC treatment (2 g/kg b.w.) three times a week for 3 weeks. The PC intoxication altered the serum biomarkers, the oxidative status, and the Tumor necrosis factor alpha (TNF-α), Bax and Bcl-2 protein expressions of tested animals. …”

Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury by Fazle Rakib (5768069)

“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”

Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis by HASHEM ABU SERHAN (19737499)

“…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …”