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821
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
منشور في 2023"…<h3>Purpose</h3><p dir="ltr">To investigate real-world prescribing trends and clinical outcomes based on body mass index (BMI) categorization in patients who received rivaroxaban therapy.…"
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822
Evaluation of the durability and shielding properties of high-strength concrete incorporating locally available materials and carbon additives
منشور في 2026"…The inclusion of steel fibers (FLDUNE) increased 28-day compressive and flexural strengths by 3.5 and 22%, respectively, and reduced shrinkage and creep by 25 and 10%. …"
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823
On the Performance of the Node Control Volume Finite Element Method for Modeling Multi-phase Fluid Flow in Heterogeneous Porous Media
منشور في 2020"…Large artificial fluid smearing is observed in coarse meshes; however, it decreases with the increase in mesh resolution. These findings prompt the use of high-resolution meshes for the method and the need for development of novel numerical methods to address this unphysical flow.…"
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824
Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
منشور في 2009"…Conversely, ABCG2 expression studied on brain capillaries from MPTP-treated mice was decreased (1.3-fold, p<0.05) and ABCB1 expression increased (1.43-fold, p<0.05) as an off-setting of brain transport. …"
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825
Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis
منشور في 2023"…<h3>Background</h3><p dir="ltr">Chronic subdural hematoma (CSDH) represents one of the most common neurologic disorders in the elderly. …"
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826
The immune landscape of solid pediatric tumors
منشور في 2022"…Upregulation of the WNT/Beta-catenin pathway was associated with unfavorable outcomes and decreased T-cell infiltration in OS.</p><h3>Conclusions</h3><p dir="ltr">We demonstrated that extracranial pediatric tumors could be classified according to their immune disposition, unveiling similarities with adults’ tumors. …"
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827
Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
منشور في 2024"…<h3>Background</h3><p dir="ltr">Cryptorchidism and testicular torsion (TT) are relatively common conditions in clinical practice; however, sparse information about cryptorchid TT is available in the current literature.…"
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828
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
منشور في 2020"…<h3>Background</h3><p dir="ltr">Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. …"
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829
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
منشور في 2020"…<h3>Background</h3><p dir="ltr">Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy bodies. …"
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830
Acute spasticity in malignant MCA stroke: a case report and review of literature
منشور في 2025"…This case emphasizes the need for awareness of atypical stroke presentation and the potential role of anabolic steroids in stroke risk.…"
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831
Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity
منشور في 2021"…</p><h3>Methods</h3><p dir="ltr">A prospective, parallel study in T2D (n = 23) and controls (n = 23). …"
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832
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
منشور في 2019"…Inhibiting either Phosphatidyl inositol (3) kinase (PI3K) with Wortmannin or the mitogen-activated protein kinase extracellular-regulated kinase (MAPK ERK) with U0126 leads to the inhibition of tube formation. …"
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833
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
منشور في 2024"…<h3>Purpose</h3><p dir="ltr">To investigate the impact of digital image post‐processing algorithms on various image quality (IQ) metrics of radiographic images under different exposure conditions.…"
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834
Coats disease in Saudi Arabia
منشور في 2012"…The reason for presentation was decreased vision in 11 cases (55 %), strabismus in 4 (20 %), leukocoria in 2 (10 %), and others in 3 (15 %) . …"
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835
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
منشور في 2010"…Administration of sphingosine decreased the ceramide-to-S1P ratio in the lung and inhibited alveolar space enlargement, along with activation of prosurvival signaling pathways and decreased lung parenchyma cell apoptosis. …"
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836
Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis
منشور في 2025"…There was no significant difference in the safety outcomes (major and minor bleeding events), with a trend towards a decreased risk among direct oral anticoagulant treated cohorts (OR 0.3, 95% CI 0.08–1.1) and (OR 0.64, 95% CI 0.24–1.7), respectively.…"
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837
Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome
منشور في 2020"…Her liver enzymes (Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase had decreased significantly.</p><h3>Conclusions</h3><p dir="ltr">AL amyloidosis can very rarely present as AIH-PSC overlap syndrome, manifesting with raised liver enzymes, biliary strictures, pruritis and positive liver antibodies. …"
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838
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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839
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
منشور في 2020"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"
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840
StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion
منشور في 2014"…We observed that, while the level of StarD13 expression decreases in cancer tissues compared to normal tissues, it increases as the grade of the tumor increased. …"
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