Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF حسب Jabr, Vanessa

"…Indeed, we showed that short-term voluntary wheel running increases the protein expression levels of the autophagy marker, protein light chain 3 (LC3B), in the hippocampus of 10-week-old mice. …"
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Why some firms export? An empirical analysis for manufacturing firms in the MENA region حسب Fakih, Ali

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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …"
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Frugal innovation for sustainable rural development حسب Mokter, Hossain

"…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …"
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Production of self-compacting concrete using Jordanian oil shale ash حسب Ashteyat, Ahmed

"…The binder materials content was kept constant at (350 kg/m3) while the water-to-binder ratio was changed from 0.5 to 0.68 depending upon the amount of mixing water needed to achieve the required fresh properties. …"
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Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management حسب Tarraf, Vanessa

"…The results displayed Nano metric size range for azithromycin-loaded uncoated and coated liposomes of values 65.5± 2.83 nm and 73.53 ± 2.01 nm, respectively with uni-modal particle size distribution with PDI less than 0.3. The shifting of the negative charge (-17.22± 5.99 mV) of the uncoated liposomes to the positive charge (13.17± 3.34 mV) of the coated one approved the success of the coating. …"
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Removal of copper ions from aqueous solution using NaOH-treated rice husk حسب Shagufta Zafar (10027380)

"…Up to 97% Cu removal was achieved in ct of 30 min using Dad of 0.3 g [Cu]i of 25 mg L−1 and T = 280 K. The ads of Cu on TRH is endothermic, spontaneous, follows Langmuir isotherms, and exhibited a PSO kinetics. …"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …"
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Coping mechanisms among Lebanese first-time college students حسب Doumit, Rita

"…As the usage of withdrawal coping strategies, being exposed to stress related to self and uncertainty increased, the well-being of Lebanese first-time college students decreased. The final regression model accounted for 54% of the variance in well-being level (52.7% adjusted) (p < .001). …"
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Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments حسب Gunjan Dagar (9339276)

"…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Translational Medicine<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12967-023-04292-3" target="_blank">https://dx.doi.org/10.1186/s12967-023-04292-3</a></p>…"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Molecular Cancer<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12943-020-01294-3" target="_blank">https://dx.doi.org/10.1186/s12943-020-01294-3</a></p>…"

Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden حسب Farra, Anna

"…Cotrimoxazole resistance has also been increasing significantly in most hospitals, in spite of decreasing sales of cotrimoxazole and trimethoprim. …"
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells حسب Homaidan, Fadia R.

"…Aim: To determine whether ceramide induces apoptosis in IEC. Methods: Apoptosis was evaluated by annexin-Vbinding or Hoechst nuclear staining. …"
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Open carbon frameworks - a search for optimal geometry for hydrogen storage حسب Kuchta, Bogdan

"…From an analysis of an analytical model and simulations of adsorption the physical limits of hydrogen adsorption have been defined: (i) higher storage capacities in slit-shaped pores can be obtained by fragmentation/truncation of graphene sheets into nano-metric elements which creates surface areas in excess of 2600 m2/g, the surface area for infinite graphene sheets; (ii) the positive influence of increasing surface area is compensated by the decreasing energy of adsorption in the carbon scaffolds of nano-metric sizes; (iii) for open carbon frameworks (OCF) built from coronene and benzene molecules with surface areas 6500 m2 g-1, we find an impressive excess adsorption of 75–110 g H2/kg C at 77 K, and high storage capacity of 110–150 g H2/kg C at 77 K and 100 bar; (iv) the new OCF, if synthesized and optimized, could lead to required hydrogen storage capacity for mobile applications.…"
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Prevention of carcinogen-induced mouse skin papilloma by Daucus carota (wild carrot) aqueous extract حسب Mroueh, M.

"…Intraperitoneal treatment decreased hyperplasia and dermal infiltration with an increase in the level of hyperkeratosis. …"
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Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs حسب Manaal Siddiqui (18891637)

"…<p dir="ltr">Purpose: This study aimed to assess the potential of flavonoids in combating CIPN. Methods: PubMed and Google Scholar were used, and studies that investigated flavonoids in models of CIPN and models of neuropathic pain similar to CIPN were included. …"

State of Global Financial Crime In-­depth Analysis on GCC Countries حسب Odeh, Layan Mazen

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Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties حسب Al Zaabi, Alanood

"…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …"
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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease حسب Satra Nim (11540447)

"…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). We show that α-synuclein impedes endolysosomal activity via this interaction, thereby inhibiting its own degradation. …"