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921
Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
منشور في 2003"…The present study was designed to verify if human (h) Angiotensin II (Ang II) type-1 receptor (hAT1R) undergoes internalization, nuclear translocation, and de novo synthesis in primary culture of human aortic vascular smooth muscle cells (hVSMCs) and if overexpression of this receptor modulates sustained free cytosolic ([Ca]c) and nuclear ([Ca]n) calcium. 3-dimensional (3-D) confocal microscopy was used to monitor free intracellular Ca2+ and hAT1R-green fluorescence protein (GFP) fusion protein in cultured hVSMCs. …"
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article -
922
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
منشور في 2025"…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …"
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923
Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
منشور في 2010"…Methods: A lentivirus was used to induce expression of the photoactivatable cationic channel channelrhodopsin-2 (ChR2) by RVLM Phox2b-containing neurons, a population that consists of central chemoreceptors (the ccRTN neurons) and blood pressure (BP)-regulating neurons (the C1 cells). …"
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article -
924
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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article -
925
Fracture Behavior of ASTM A633 steel plate specimens with edge crack at tensile test
منشور في 2017"…Experimental analysis is used to analyze the loaddisplacement curve, and fracture surface around the crack. Also Finite Element Method (FEM) is used to see the J-integral curve for various crack lenghs. …"
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conferenceObject -
926
Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: Is the treated wastewater safe to reuse for agricu...
منشور في 2015"…The treatment process achieved 3.5 logs removal of heterotrophic bacteria and up to 3.5 logs removal of fecal coliforms. …"
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article -
927
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
منشور في 2025"…Moreover, the overactivity of glycogen synthase kinase-3 beta (GSK-3β) also triggers taurine protein pathology. …"
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928
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
منشور في 2023"…The collective’s role in fostering social support was evident through decreased fearful reactions. Many lost trust in the judicial system and favored emigration over standing for justice. …"
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article -
929
Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
منشور في 1991"…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …"
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article -
930
Bulk passivation of perovskite films utilizing halide anion ionic liquids
منشور في 2023"…These values show that the presence of the IL with chloride anion greatly improves the average lifetime of the charge carrier by around 250%, while IL with iodide anion decreased the lifetime by 32% as compared with the pristine perovskite sample. …"
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article -
931
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
منشور في 2021"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …"
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article -
932
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
منشور في 2024"…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …"
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article -
933
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
منشور في 2023"…Additionally, IL-35 or THYO decreased TNF-α, NF-κB, IL-10, IL-6 and IFN-γ in contrast to the PAR control group. …"
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934
Zirconium Phosphate/Ionic Liquid Proton Conductors for High Temperature Fuel Cell Applications
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doctoralThesis -
935
Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful?
منشور في 2009"…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …"
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article -
936
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937
Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust
منشور في 2020"…Atmospheric dust in Qatar is depleted in Al and enriched in calcium (Ca), in the form of calcium carbonate (CaCO<sub>3</sub>), relative to the global average Upper Continental Crust (UCC). …"
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938
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
منشور في 2016"…In this study, the first order second moment reliability method is used to evaluate network reliability. This paper presents a numerical example that shows the result of ignoring uncertainties after a disaster is overestimated. …"
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article -
939
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
منشور في 2021"…The lowest number of functional groups occurred in the early ages (2–3 years old), and some groups either increased or decreased their frequency and abundance along the years. …"
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940
Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
منشور في 2016"…Purpose To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Patients and methods Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated. …"
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article