The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... by Thozhukat Sathyapalan (704787)

“…There was a significant positive correlation between ASP levels with CRP (p < 0.01), testosterone (p < 0.01) and HOMA-IR (p < 0.01); IL-6 levels with CRP (p <0.01) and testosterone (p < 0.01) and MCP-1 with CRP (p < 0.01); testosterone (p < 0.01) and HOMA-IR (p < 0.02).</p><h3>Conclusions</h3><p dir="ltr">This post-hoc analysis revealed that 12 weeks of atorvastatin treatment significantly decreased the markers of adipose tissue dysfunction and inflammation, namely ASP, IL-6 and MCP-1 in obese women with PCOS. …”

Production of self-compacting concrete using Jordanian oil shale ash by Ashteyat, Ahmed

“…The binder materials content was kept constant at (350 kg/m3) while the water-to-binder ratio was changed from 0.5 to 0.68 depending upon the amount of mixing water needed to achieve the required fresh properties. …”
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Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride by A. Bahgat Radwan (9631720)

“…Herein, the inhibition efficiency of a new corrosion inhibitor, behentrimonium chloride (BTC, C25H54ClN), is explored in a simulated-concrete pore solution (SCP) with 3.5 wt.% NaCl at different pH using electrochemical impedance spectroscopy (EIS) and polarization methods. …”

Removal of copper ions from aqueous solution using NaOH-treated rice husk by Shagufta Zafar (10027380)

“…Up to 97% Cu removal was achieved in ct of 30 min using Dad of 0.3 g [Cu]i of 25 mg L−1 and T = 280 K. The ads of Cu on TRH is endothermic, spontaneous, follows Langmuir isotherms, and exhibited a PSO kinetics. …”

A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter by Ahmad Khan (6067526)

“…<h3>Abstract</h3><p dir="ltr">This paper presents a method for improving the reliability of DC nanogrids by decreasing the input capacitance requirement. …”

Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study by Stefanos Volianitis (22155835)

“…Arterial ammonia increased in parallel to lactate from 47.3 (40.1–54.5) to 144.4 (120.5–168.3) μmol/L (<i>P</i> < 0.05), although hepatic ammonia uptake increased from 19.5 (12.4–26.6) to 69.5 (46.5–92.5) μmol/min (<i>P</i> < 0.05). …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... by Amir Vahedian-Azimi (11177056)

“…<h3>Background</h3><p dir="ltr">The impact of the chronological sequence of events, including cardiac arrest (CA), initial cardiopulmonary resuscitation (CPR), return of spontaneous circulation (ROSC), and extracorporeal cardiopulmonary resuscitation (ECPR) implementation, on clinical outcomes in patients with both out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA), is still not clear. …”

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…When performed within 4 weeks of chemotherapy, PET had a negative predictive value of 13.3% and a positive predictive value of 94.3%. The sensitivity was 89.9%, the specificity was 22.2%, and the accuracy was 85.5%. …”
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Recyclable polyaspartate-coated magnetic nanoparticles for sustainable control of calcite and barite scales in oilfield operations by Abdelrahman T. Abdelaal (14674629)

“…<p dir="ltr">Scale formation is a major challenge in hydrocarbon production, leading to decreased efficiency, equipment damage, and increased operational costs. …”

Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Gunjan Dagar (9339276)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Translational Medicine<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12967-023-04292-3" target="_blank">https://dx.doi.org/10.1186/s12967-023-04292-3</a></p>…”

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy by Ajaz A. Bhat (12984701)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Molecular Cancer<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12943-020-01294-3" target="_blank">https://dx.doi.org/10.1186/s12943-020-01294-3</a></p>…”

Prevention of carcinogen-induced mouse skin papilloma by Daucus carota (wild carrot) aqueous extract by Mroueh, M.

“…Intraperitoneal treatment decreased hyperplasia and dermal infiltration with an increase in the level of hyperkeratosis. …”
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients by Asmaa Al-mansouri (16931739)

“…There was a strong negative correlation between TBQ score and KDQOL-36™ score [rs (251) = −0.616, p < 0.001], signifying that HR-QOL decreases as treatment burden increases.</p><h3>Conclusions</h3><p dir="ltr">This study suggests that a considerable proportion of CKD patients suffered from treatment-related burden and deterioration in HR-QOL at a varying degree of seriousness. …”

Recovery of business intelligence systems by Haraty, Ramzi A.

“…Saving the damage assessment time means shorter denial of service periods, which in turn guarantees the continuity of the patient centric healthcare system.…”
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A component analysis of positive behaviour support plans by Grey, Ian

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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). We show that α-synuclein impedes endolysosomal activity via this interaction, thereby inhibiting its own degradation. …”

Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells by Sleiman, S.

“…The present study was designed to verify if human (h) Angiotensin II (Ang II) type-1 receptor (hAT1R) undergoes internalization, nuclear translocation, and de novo synthesis in primary culture of human aortic vascular smooth muscle cells (hVSMCs) and if overexpression of this receptor modulates sustained free cytosolic ([Ca]c) and nuclear ([Ca]n) calcium. 3-dimensional (3-D) confocal microscopy was used to monitor free intracellular Ca2+ and hAT1R-green fluorescence protein (GFP) fusion protein in cultured hVSMCs. …”
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One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes by Goran Petrovski (129836)

“…The participants used the sensor 88.4 ± 6.5% of the time with Auto Mode usage 85.6 ± 7.4% during 12 months of HCL system use. HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline, to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at 3 months (p = 0.02) and remained stable to 7.1 ± 0.6 (54 ± 6.6 mmol/mol) at 12 months (p = 0.02). …”

Breaking the barriers towards large-scale microalgae-based bio-hydrogen production by Isra Koko (22631396)

“…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …”