Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.</p><h3>Results</h3><p dir="ltr">After confirming the previously reported correlation between methylation of SLFN11 promoter and its expression across multiple cell lines, we showed in-vitro that decitabine and IFN-γ could increase moderately the expression of SLFN11 in both BT-549 and T47D cell lines. …”

Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar by John M., Rivers

“…These offshore-migrating eolian-derived sediments are being redistributed by tidal currents in an otherwise low-energy coastal zone, where in situ formation of carbonate mud and a low-diversity skeletal assemblage is ongoing within salinity-restricted environments. Three depositional sectors are delineated: 1) an energetic, linear, fault-controlled Entrance Channel into which the eolian dunes spill directly; 2) a relatively deep (up to 20 m) Outer Lagoon, interpreted to represent a flooded karst-collapse structure; and 3) a sprawling, low-energy, shallow (<2 m) Inner Lagoon occupying low-lying areas between deflated eolian dunes.Physical oceanographic modeling, integrating multi-seasonal current meter and tidal gage measurements, demonstrates tidal current flow velocities are relatively high in both the Entrance Channel and at the constricted entrance to the Inner Lagoon. …”
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases by Yousef Yahia (19756989)

“…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…”

Storage allocation for diverse FPGA memory specifications by Ouaiss, Iyad

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Testing and Evaluation of a Smart Irrigation System Towards Smart Landscaping in UAE by Al Sulaimani, Fatma

“…The outcomes of the use of SMS have shown better results in water conservation, 21%, and 26% decrease in water consumption for the months of September and October, respectively.…”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

“…This paper illustrates the many strategies to bridge the deficiency energy gap in three categories; 1) increase PV panel energy production by optimizing the orientation, inclination angle, manual tracking, enhanced microcontrollers and inverters, 2) increase PV panel efficiency from better manufacturers, 3) increase the area of PV panel installation on the building fabric and exploring options beyond the building footprint at the community level. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. …”

Full Film, Boundary Lubrication and Tribochemistry in Steel Circular Contacts Lubricated with Glycerol by Habchi, W.

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The impact of maternal care on child development by Sayour, Nagham

“…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …”
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Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine by Salman M. Toor (8854751)

“…Therefore, there is a real need to explore novel candidates of vaccine development and decrease mortality rates.…”

Writing and publishing language studies in the Arab region [Khitabaat Journal] by Emad Abdul-latif (21841985)

“…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …”
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Sustainable Concrete Mix Design: Experimental Study of Life-Size Columns by Abboud, Steven G.

“…This study addresses the use of a unique 3-part substation made from those materials, as well as the life-sizing of Sustainable mixes, which is not highlighted in previous research. …”
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Fixed-interval versus OCT-guided variable dosing of intravitreal bevacizumab in the management of neovascular age-related macular degeneration by El-Mollayess, Georges M.

“…Similarly, CRT decreased after 12 months by 80.7 μm for variable dosing vs 100.5 μm for fixed-interval dosing (P = .37). …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach by Hoda, Hosseini

“…Overall, due to the increasing bacterial concentration, considerations limiting bacterial contamination need to be taken.…”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …”
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Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar by Suhaila Ghuloum (796180)

“…Stigmatizing attitudes by HCP can have adverse consequences on people with mental illness from delays in seeking help to decreased quality of care provided. Assessing such attitudes is an essential step in understanding such stigma and, if needed, developing and testing appropriate and culturally adapted interventions to reduce it.…”

Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting by Ananth Nazarene (21239912)

“…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …”

Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients by Bouquet, Antoine

“…Surgical resection of all tumor sites is the only treatment that enables prolonged survival, but the synchronous presentation of CLM has been associated with poor outcomes.1 Preoperative chemotherapy is widely used in these patients to provide early treatment of metastatic disease, to improve patient selection for surgical resection,2 and 3 and to decrease the recurrence rate after surgery.4 The traditional surgical strategy for patients with resectable synchronous CLM includes resection of the primary tumor followed by chemotherapy and then liver resection. …”
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A survey on communication technologies and requirements for internet of electric vehicles by Islam Safak Bayram (18421482)

“…<p>Electric vehicles (EVs) are becoming a more attractive transportation option, as they offer great cost savings, decrease foreign oil dependency, and reduce carbon emissions. …”