PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Indeed the ratio of PRX302 to proaerolysin cleavage by PSA was more than 40 times that of any other protease tested. As expected, native proaerolysin was effectively cytotoxic at low pM concentrations in all cells tested (LNCaP, DU145, CWR22Rvi, PC3, PrEC, and RWPE2-W99). …”
Get full text
Get full text
Get full text

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…Moreover, the overactivity of glycogen synthase kinase-3 beta (GSK-3β) also triggers taurine protein pathology. …”

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…<h3>Background </h3><p dir="ltr">Polypharmacy has become a global public health concern particularly in the elderly population. …”

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…</p><h3>Results </h3><p dir="ltr">Out of 5639 patients screened, 75.5% (95% CI: 74.3–76.6) were exposed to polypharmacy. …”

The Effect of Chitosan’s Addition to Resorcinol/Formaldehyde Xerogels on the Characteristics of Resultant Activated Carbon by Ahmed Awadallah-F (825837)

“…The total pore volume decreased from 1.040 to 0.238 cm3/g and the total pore surface area decreased from 912.3 to 554.4 m2/g. …”

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…<h3>Background</h3><p dir="ltr">Ending the global tobacco epidemic is a defining challenge in global health. …”

How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly by Ramada R. Khasawneh (6837734)

“…</p><h3>Methods</h3><p dir="ltr">The study enrolled 232 subjects, evaluated using plain radiographs. …”

PP245-SUN: Outstanding abstract by Bassil, M.

Get full text
Get full text
Get full text
Get full text

LDL-C Targets in Secondary Prevention: How Low Should We Go? by Karim Bayoumy (3496688)

“…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …”

Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System by Bair, Scott

“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
Get full text
Get full text
Get full text
Get full text

The Effect of DJ-1 on Invasion and Invadopodia Formation in Glioblastoma Multiforme by Ezzeddine, Aya

“…DJ-1 is an oncogene which stimulates cell proliferation by inhibiting the tumor suppressor PTEN and leads to the subsequent activation of the PI3Kinase pathway. We have shown in the lab that DJ-1 knockdown decreases 2D cell motility of breast cancer cells. …”
Get full text
Get full text
Get full text

Protein and pH-dependent Binding of Nascent Pectin and Glucuronarabinoxylan to Xylogucan in Pea by Rizk, Sandra

“…The binding was maximum at low pH (3–4), and decreased to almost zero at pH 6. The binding was probably non-covalent and reached saturation within 5 min. …”
Get full text
Get full text
Get full text

NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides by Kabbani, Ahmad T.

“…The interaction of several high-spin p-substituted tetraphenylporphinato-iron(III) halide complexes (p-R-TPPFeX) with the aromatic π acceptor, 1,3,5-trinitrobenzene (TNB) has been studied by proton and 13C NMR. …”
Get full text
Get full text
Get full text

Chemical and microbiological investigations of metal ion interaction with norfloxacin by Na'was, T. E.

“…This report describes a spectrophotometric study on the interaction between norfloxacin (NFX) and metal ions (Al3+, Mg2+ and Ca2+). Two buffers of pH 3.6 and 8.8 were used. …”
Get full text
Get full text
Get full text

Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma by AbouAntoun, Thamara Jihad

“…PDGF-BB treatment of cells enhanced migration and proliferation after 24 hr; increased PDGFRβ, PI3K, Akt and Erk1/2 activity, decreased PTEN activation and transactivated EGFR. …”
Get full text
Get full text
Get full text

The DJ-1 superfamily members YhbO and YajL from Escherichia coli repair proteins from glycation by methylglyoxal and glyoxal by Abdallah, Jad

“…Bacterial extracts from deglycase mutants display increased glycation levels, whereas deglycase overexpression decreases protein glycation. Moreover, yhbO and yajL mutants display decreased viability in methylglyoxal- or glucose-containing media. …”
Get full text
Get full text
Get full text
Get full text

Treatment sequencing strategy for hepatic epithelioid haemangioendothelioma by Thomas, Ryan

“…However, 5-year survival for patients treated with chemotherapy at any point during their disease course was decreased compared with those who did not receive any chemotherapy (43.6% versus 82.9%, respectively; P = 0.02) and was predictive of a decreased overall survival on univariate analysis [HR 3.1 (CI 0.9–10.7), P = 0.02]. …”
Get full text
Get full text
Get full text

Hypoglossal nerve stimulation for obstructive sleep apnea in adults: An updated systematic review and meta-analysis by Warda A. Alrubasy (18021700)

“…Patient-reported outcomes showed decreased Epworth Sleepiness Scale (ESS) scores by −5.02 (short term) and −4.90 (long term) and improved Functional Outcomes of Sleep Questionnaire (FOSQ) scores by 3.58 (short term) and 3.28 (long term). …”

Microbiota and sensorial attributes of buffalo meat stored under vacuum packaging: combined impact of marination, citrox and oregano essential oil by Tareq Osaili (11550286)

“…The combination of citrox and oregano essential oil (EO) resulted in decreases of 3.0–6.8 and 3.2–6.8 log cfu/g for mesophilic aerobic bacteria, Pseudomonas spp. lactic acid bacteria (LAB), Brochothrix thermosphacta, Enterobacteriaceae, and yeasts, at 4 and 12°C, respectively. …”

Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection? by Abu Saleh Md Moin (6189512)

“…<h3>Background</h3><p dir="ltr">Women with polycystic ovary syndrome (PCOS) often have vitamin D deficiency, a known risk factor for severe COVID-19 disease. …”