Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration by Milane, Aline

“…Conversely, ABCG2 expression studied on brain capillaries from MPTP-treated mice was decreased (1.3-fold, p<0.05) and ABCB1 expression increased (1.43-fold, p<0.05) as an off-setting of brain transport. …”
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Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis by Mohammed Maan Al-Salihi (13105835)

“…<h3>Background</h3><p dir="ltr">Chronic subdural hematoma (CSDH) represents one of the most common neurologic disorders in the elderly. …”

The immune landscape of solid pediatric tumors by Shimaa Sherif (12862990)

“…Upregulation of the WNT/Beta-catenin pathway was associated with unfavorable outcomes and decreased T-cell infiltration in OS.</p><h3>Conclusions</h3><p dir="ltr">We demonstrated that extracranial pediatric tumors could be classified according to their immune disposition, unveiling similarities with adults’ tumors. …”

Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials by Yara Wanas (8744844)

“…<h3>Background</h3><p dir="ltr">Angiotensin receptor blockers (ARBs) are commonly used as a treatment for many cardiovascular diseases, but their safety has been called into question. …”

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts by Mustafa T. Ardah (4858657)

“…<h3>Background</h3><p dir="ltr">Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy bodies. …”

Conflict in Ukraine and the unsettling ripples: implications on food systems and development in North Africa by Tarek Ben Hassen (15742605)

“…The consequent high fertilizer prices have also affected local food production, decreasing yields and increasing food prices. However, those countries with substantial financial resources (cf. …”

Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates by Fariha Niaz (14778319)

“…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …”

Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity by Abu Saleh Md Moin (6189512)

“…</p><h3>Methods</h3><p dir="ltr">A prospective, parallel study in T2D (n = 23) and controls (n = 23). …”

RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells by El Atat, Oula

“…Inhibiting either Phosphatidyl inositol (3) kinase (PI3K) with Wortmannin or the mitogen-activated protein kinase extracellular-regulated kinase (MAPK ERK) with U0126 leads to the inhibition of tube formation. …”
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Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden by Farra, Anna

“…Cotrimoxazole resistance has also been increasing significantly in most hospitals, in spite of decreasing sales of cotrimoxazole and trimethoprim. …”
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells by Homaidan, Fadia R.

“…Results: IL-1 increased ceramide accumulation in a time-dependent and concentration-dependent manner with a peak response at 4 h, with [IL-1] = 30 ng/ml. …”
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Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images by Ioannis A. Tsalafoutas (14776939)

“…<h3>Purpose</h3><p dir="ltr">To investigate the impact of digital image post‐processing algorithms on various image quality (IQ) metrics of radiographic images under different exposure conditions.…”

Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review by Amani N. Alansari (19743643)

“…Academic impacts included increased absenteeism (24–29%) and decreased performance.</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">This review highlights the widespread prevalence and serious consequences of bullying among adolescents in AGC, with clear gender differences and significant impacts on mental health and academic performance. …”

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study by Richard Charles Franklin (9154052)

“…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …”

Coats disease in Saudi Arabia by Alqahtani, Abdullah A.

“…The reason for presentation was decreased vision in 11 cases (55 %), strabismus in 4 (20 %), leukocoria in 2 (10 %), and others in 3 (15 %) . …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…Administration of sphingosine decreased the ceramide-to-S1P ratio in the lung and inhibited alveolar space enlargement, along with activation of prosurvival signaling pathways and decreased lung parenchyma cell apoptosis. …”
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Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis by Mohamed Nabil Elshafei (9960500)

“…There was no significant difference in the safety outcomes (major and minor bleeding events), with a trend towards a decreased risk among direct oral anticoagulant treated cohorts (OR 0.3, 95% CI 0.08–1.1) and (OR 0.64, 95% CI 0.24–1.7), respectively.…”

Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome by Hammad Shabir Chaudhry (20376378)

“…Her liver enzymes (Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase had decreased significantly.</p><h3>Conclusions</h3><p dir="ltr">AL amyloidosis can very rarely present as AIH-PSC overlap syndrome, manifesting with raised liver enzymes, biliary strictures, pruritis and positive liver antibodies. …”

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

“…From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. …”
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Effect of water extract of Althaea officinalis flowers on inflammation, gastric ulcer, bacterial activity, platelet aggragation, glycemia, and lipidemia. (c2006) by Hage-Sleiman, Rouba

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