Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes حسب Abi-Gerges, Aniella

"…In an attempt to address this question, 3 weeks-old rats were subjected to aortic coarctation (H) or sham operated (S). 5 weeks after surgery, the mass of the left ventricle to tibia length ratio was 59% increased in the H group compared to the S group while the right ventricle mass to tibia length ratio was unchanged, attesting compensated hypertrophy of the heart in H rats. …"
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Optimizing clopidogrel dose response حسب Saab, Yolande B.

"…To get a therapeutic effect and avoid adverse drug reactions, therapeutic dose of 75 mg clopidogrel, for example, should be lowered to 6 mg or increased to 215 mg in patients with different genotypes. …"
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Techno-economic assessment of building energy efficiency systems using behavioral change: A case study of an edge-based micro-moments solution حسب Yassine Himeur (14158821)

"…<p dir="ltr">Energy efficiency based on behavioral change has attracted increasing interest in recent years, although, solutions in this area lack much needed techno-economic analysis. …"

Anomaly Detection on Smart Grids With Optimized Convolutional Long Short-Term Memory Model حسب Ahmad N. Alkuwari (22392226)

"…<p dir="ltr">The integration of digital technologies into traditional power systems has increased the efficiency and sustainability of power grids, transforming traditional grids into smart grids. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. Thus, the anticancer effects of Pt/MgO nanoparticles were attributed to the induction of oxidative stress and apoptosis. …"

A Comprehensive Review of the COVID-19 Pandemic and the Role of IoT, Drones, AI, Blockchain, and 5G in Managing its Impact حسب Vinay Chamola (16870059)

"…The number of laboratory-confirmed coronavirus cases has been increasing at an alarming rate throughout the world, with reportedly more than 3 million confirmed cases as of 30 April 2020. …"

From past famines to present crises: The epigenetic impact of maternal malnutrition on offspring health in Gaza حسب Mohamed Adil Shah Khoodoruth (14589828)

"…It was shown that first-trimester exposure to severe famine during the Dutch Hunger Winter was associated with increased risk of schizophrenia in offsprings (Hoek et al., 1998). …"

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy حسب Nassiba Taib (14557385)

"…</p><h2>Results</h2><p dir="ltr">DAC treatment significantly upregulated stemness markers in both primary 1076 Col and meta-static 1872 Col cell lines, although a lower effect occurred on the latter: CD44 (7.85 fold; ***p = 0.0001 vs. (4.19 fold; *p = 0.0120), Nanog (4.1 fold; ***p < 0.0001 vs.1.69 fold; ***p = 0.0008), KLF-4 (4.33 fold; ***p < 0.0001 vs.2.48 fold; ***p = 0.0005), CD133 (16.77 fold; ***p = 0.0003 vs.6.36 fold; *p = 0.0166), and MSI-1 (2.33 fold; ***p = 0.0003 vs.2.3 fold; ***p = 0.0004), respectively. Interestingly, in the metastatic 1872 Col cells treated with DAC, the expression of both PD-L1 and NY-ESO-1 was increased tenfold (*p = 0.0128) and fivefold (***p < 0.0001), respectively.…"

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... حسب Bogachev, Oleg

"…Consistently, ablation of AEBP₁ results in significant attenuation of atherosclerosis (males: 3.2-fold, P = 0.001 (en face)), 2.7-fold, P = 0.0004 (aortic roots); females: 2.1-fold, P = 0.0026 (en face), 1.7-fold, P = 0.0126 (aortic roots)) in the AEBP₁⁻′⁻/low-density lipoprotein receptor (LDLR)⁻′⁻ double-knockout (KO) mice. …"
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Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury حسب Judith, Nwaiwu

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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In addition to highlighting the role of the R162 residue in NLuc activity, we believe that the mutant NLuc will find wide application in designing in vitro assays requiring extended monitoring of NLuc bioluminescence activity. </p><h3>Significance </h3><p dir="ltr">Bioluminescence has been extensively utilized in developing a variety of biological and biomedical assays. …"

Using fuzzy reasoning to improve redundancy elimination for data deduplication in connected environments حسب Yakhni, Sylvana

"…The Internet of Things is ushering in the era of connected environments where the number and diversity of data sources (devices and sensors) are inevitably increasing the size of the data that need to be stored locally (at the edge device level) and transmitted to base storages (at the sink level) of the network. …"
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In vitro regulation of quorum sensing in Pseudomonas aeruginosa using synthetic autoinducers By Hrag Dilabazian A thesis حسب Dilabazian, Hrag

"…The lasI and rhlI gene products respectively drive the synthesis of N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL) and N-butyryl homoserine lactone (BHL), the autoinducers of Pseudomonas aeruginosa. …"
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Extended hepatectomy in patients with hepatobiliary malignancies with and without preoperative portal vein embolization حسب Abdalla, Eddie

"…After PVE, FLR volumes increased significantly (P = .003); preoperative FLR volumes were similar in both groups (patients who underwent PVE, 25%; and patients who did not undergo PVE, 23%). …"
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Levels and indoor–outdoor relationships of PM10 and soluble inorganic ions in Beirut, Lebanon حسب Saliba, N.A.

"…The observed high intra-site temporal variation (minimum of 34 and a maximum of 120 μg/m3) was attributed to the dynamic air masses passing over the Eastern Mediterranean region. …"
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Coevolving residues distant from the ligand binding site are involved in GAF domain function حسب Wesam S. Ahmed (10170053)

"…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …"

Optimizing chemisorption based direct air capture unit efficiency in HVAC systems: A study on the impact of DAC location and adsorption conditions as a response to the climate cris... حسب Yasser M. Abdullatif (16500945)

"…Specifically locating DAC unit at Position 6 increases DAC efficiency from 5.3% to 27.19% for 8th of June 2022 at 11:00 am in Qatar. …"

Sensitivity analysis and genetic algorithm-based shear capacity model for basalt FRC one-way slabs reinforced with BFRP bars حسب Abathar Al-Hamrani (16494884)

"…<p dir="ltr">Fiber-reinforced polymer (FRP) composites are increasingly used in concrete structures owing to their superior corrosion resistance. …"

Inhibition of T-cell activity in alopecia areata: recent developments and new directions حسب Thierry Passeron (6995899)

"…Few treatment options are available, with the Janus kinase (JAK) 1/2 inhibitor baricitinib (2022) and the selective JAK3/tyrosine kinase expressed in hepatocellular carcinoma (TEC) inhibitor ritlecitinib (2023) being the only US Food and Drug Administration–approved systemic medications thus far for severe AA. …"

Akkermansia, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar حسب Arun Prasath Lakshmanan (16444663)

"…We recruited 28 T1DM subjects with an average age of 10.5 ± 3.53 years. The stool sample was used to measure microbial composition by 16s rDNA sequencing method. …"