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481
Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes
منشور في 2023"…Previous studies have revealed changes in gene expression patterns, disruptions in cellular signaling pathways, and increased oxidative stress resulting from e-cigarette exposure. …"
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482
Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
منشور في 2022"…Oxidative stress (OS) has been shown to have a negative effect on the autonomic nervous system (ANS) and on ANS modulation of heart rate. …"
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483
Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
منشور في 2022"…<div><p>The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin resistance and vascular complications in diabetes. Consequently, the increased flux of glucose metabolism without a change in the expression and activity of glycolytic enzymes produces a wave of increased glycolytic intermediates driving mitochondrial dysfunction and increased reactive oxygen species (ROS) formation, the activation of hexosamine and protein kinase C pathways, the increased formation of methylglyoxal-producing dicarbonyl stress, and the activation of the unfolded protein response. …"
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484
Applications, advancements, and challenges of cyanobacteria-based biofertilizers for sustainable agro and ecosystems in arid climates
منشور في 2024"…<p>Based on the increasing world population, the food demands have tremendously increased. …"
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485
Unveiling final-year students and new graduates’ concerns, preparedness, and learning experiences during the pandemic in Qatar: A cross-sectional survey
منشور في 2023"…While 61 % of new graduates felt well-prepared in their nursing skills, and 87 % felt confident, less than half of the students still in their final year of education felt prepared or confident. Increased stress and a perceived impact on education quality were reported due to changes in learning modalities. …"
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486
Using GIS and optimization to manage construction and demolition waste: The case of abandoned quarries in Lebanon
منشور في 2019"…Increased stress on raw material and limited landfill space due to increasing rates of urbanization have encouraged efforts to divert Construction and Demolition Waste (C&DW) away from landfills toward sorting, recycling, and reusing. …"
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487
Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia
منشور في 2021"…Dementia is a recognized complication of type 2 diabetes (T2D) with an increasing prevalence, and AD is the most common cause. …"
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488
Enhancement of polysulfone ultrafiltration membrane with third generation poly(amido amine)-graphene oxide nanocomposite
منشور في 2023"…The abundance of -OH and -NH2 groups on the synthesized nanocomposites resulted in improved hydrophilicity of the membrane and aided improving the membrane porosity and increased its pore radius. As a result, the membrane pure water permeation flux increased by 1300 % for the new membrane compared to pristine PSF membrane to reach a maximum of 124.5 LMH/bar while maintaining a high BSA rejection rate of 99 % with a flux recovery rate of 55 %. …"
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489
Sustainable Production of Nannochloris atomus Biomass Towards Biodiesel Production
منشور في 2020"…Similarly, the lipid content was strongly influenced by the elevation of temperature; indeed, it increased up to ~3 folds when the temperature increased from 20 to 40 °C. …"
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490
The role of dietary antioxidants in type 2 diabetes and neurodegenerative disorders: An assessment of the benefit profile
منشور في 2022"…ROS is also associated with increased mitochondrial dysfunction and neuroinflammation, aggravating neurodegenerative conditions in the body, particularly with age. …"
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491
Bond durability performance of sand-coated BFRP bars in high-strength fiber reinforced concrete
منشور في 2023"…<p dir="ltr">The ever-increasing utilization of fiber-reinforced polymer (FRP) bars has led to a surge in research regarding their bonding properties with concrete. …"
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492
Numerical Evaluation of Pre-Damaged Beam Using Recycled Concrete Aggregate Strengthened by FRP Sheets
منشور في 2022"…Fiber reinforced polymer (FRP) has been increasingly used nowadays as an effective rehabilitation method in buildings due to structural flaws and aging of building structures, therefore it is an effective method to repair beams, columns, slabs. …"
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493
An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
منشور في 2022"…However, those Arabic-speaking students attending non-Arabic schools become less proficient in the Arabic language and continually fall behind their peers in Arabic schools. This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. …"
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494
Oxandrolone Treatment in Adults with Severe Thermal Injury
منشور في 2009"…Muscle protein catabolism in patients with severe thermal injury is the result of stress-induced increased release of cytokines and counterregulatory hormones. …"
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495
Ecological impacts and potential hazards of nickel on soil microbes, plants, and human health
منشور في 2024"…The contamination of agricultural soils with Ni, increases risks of its entry to terrestrial ecosystems and food production systems posing a threat to both food security and safety. …"
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496
Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
منشور في 2020"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
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497
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish
منشور في 2019"…We successfully assessed cardiac function and hemodynamic shear stress for normal as well as for diseased embryonic chicken and zebrafish. …"
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498
Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus
منشور في 2017"…Using cross-sectional regression models, a significant association was observed between higher education levels, lower levels of anxiety and depression, and reduced overall mortality in diabetic hypertensive subjects, while impaired renal function, a history of stroke and myocardial infarction, and increased alcohol and tobacco consumption were significantly associated with increased mortality. …"
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499
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
منشور في 2022"…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …"
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500
Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery
منشور في 2011"…This time delay also increases with aneurysm size and varies with heart rate and waveform.…"
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