Exploring beyond numeric weight loss: The metabolic effects of semaglutide by Sara Sokary (17337724)

“…</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …”

Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. We also concluded that autophagy was activated in response to arginine depletion and plays a protective role at early time points. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…We separated risk factors into three groups according to trajectory over time: those with a decreasing attributable burden, due largely to declining risk exposure (eg, diet high in trans-fat and household air pollution) but also to proportionally smaller child and youth populations (eg, child and maternal malnutrition); those for which the burden increased moderately in spite of declining risk exposure, due largely to population ageing (eg, smoking); and those for which the burden increased considerably due to both increasing risk exposure and population ageing (eg, ambient particulate matter air pollution, high BMI, high FPG, and high SBP). …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…Although there was a clear global decrease in the age-standardised death, and DALY rates, some countries experienced an increase in these rates. National policy makers should learn from these differences, and allocate resources for preventative measures, based on their country-specific estimates. …”

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…MethodsWe used the 2019 Global Burden of Disease (GBD) data for estimates of prevalence, years lived with disability (YLDs), and underlying causes of HF in the EMR. …”
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties by Ovidiu, Ciobanu

“…ObjectiveThe aim of this study is to investigate how hydrogen peroxide (HP) treatments affect enamel porosity and protein structure, as well as their impact on tooth shade and hardness over time. MethodsFifty healthy teeth were collected from adult patients. …”
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Burden of thyroid cancer in North Africa and Middle East 1990–2019 by Seyed Aria Nejadghaderi (11651651)

“…In 1990–2019, the overall change in thyroid cancer incident cases was a 396% increase which was mostly driven by the increase in disease-specific incidence rate (256.8%).…”

Exploring the Dynamic Interplay of Deleterious Variants on the RAF1–RAP1A Binding in Cancer: Conformational Analysis, Binding Free Energy, and Essential Dynamics by Abbas Khan (5141000)

“…Moreover, one mutation in RAF1 reported elevated levels of binding between <i>RAF1</i> and <i>RAP1P</i> while in <i>RAP1A</i>, 7 mutations were reported to increase the binding affinity. The high‐binding mutations, P34Q and V60F, were subjected to protein–protein coupling which confirmed the increase in the binding affinity. …”

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... by Parkes J Kendrick (9714851)

“…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …”

Supplementation of retrobulbar block with clonidine in vitreoretinal surgery by Abi Nader, Elie

“…Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…”
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Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in... by Ghizlane Bendriss (9025832)

“…This study showed a decrease in 2014 for the proportion of students in the foundation year that studied sciences in English with 73% in 2013 to 39% in 2014. …”

Influence of co-current vapor flow on falling film over horizontal tube by Furqan Tahir (14429547)

“…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …”

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics by Farah F. Salameh (21797300)

“…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …”

Self-Organization and Multi-Agent Reinforcement Learning for Taxi Dispatch by Alshamsi Omran, Aamena Ali Ahmed

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Does technological progress make OECDcountries greener? New evidence from panel CS-ARDL by Nghiem, Xuan-Hoa

“…CommonCorrelated Effects Mean Group (CCEMG) and Augmented Mean Group (AMG) estimators are used to test for robustness of results. …”
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System dynamics modeling for mitigating energy use and CO2 emissions of freight transport in Lebanon by Haddad, Marc

“…Previous studies showed that significant reductions in energy use and emissions can be achieved from combining mitigation strategies that improve engine technology for cars and increase the use of public transport. However, these are not sufficient to offset the growth in freight emissions, estimated to account for nearly half of total GHG emissions in 2040. …”
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Fixed-interval versus OCT-guided variable dosing of intravitreal bevacizumab in the management of neovascular age-related macular degeneration by El-Mollayess, Georges M.

“…Results Compared to baseline, variable dosing had a mean improvement in BCVA of 11.0 letters after 12 months vs 9.2 letters for fixed-interval dosing (P = .81). …”
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The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar... by Muna Abed Alah (18171346)

“…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …”

Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar by Suhaila Ghuloum (796180)

“…</p> <h3>Results</h3> <p>A total of 406 nurses and 92 doctors participated in the study. The nurses' mean MICA score was significantly higher than that of the physicians. …”