Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

"…WP1066 suppressed the phosphorylation of JAK2 and phosphorylation (Tyr705) of STAT3 in all three melanoma cell lines. In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

"…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"

Positron annihilation doppler broadening spectroscopy of carbon black and carbon black-filled rubber polymers حسب Semaan, Mars E.

"…The S parameter is found to decrease with carbon black particle and aggregate diameter, to increase with carbon black surface area, and to decrease as more carbon black is added to the polymer samples. …"
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Critical Review of Steel Column Base Plate Design Codes and Their Relevance to United Arab Emirates حسب SREENIVASAN, SREEJU

"…Structural engineers are often posed with a question for an economical design of a structural building which would decide the overall economic and the time concern in a construction. If the design is at optimum by choosing a suitable code the involvement of the materials would be less which will help to decrease the pollution caused in the environment as well. …"
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) حسب Mohammad, Hadi Ahmad

"…The results indicate that the statistical downscaling model (SDSM) is performing satisfactorily in predicting maximum and minimum temperatures, along with precipitation, for the time horizon of the simulation. Mean precipitation of 1.98 mm (RCP2.6), 2.03 mm (RCP4.5), and 2.07 mm (RCP8.5) was revealed in the study area. …"
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Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics حسب Fakher Hamdi (21225134)

"…All blends show an increase in brake mean effective pressure (BMEP) compared to B0, with the maximum enhancement observed in B10 with an average increase of 13% across all speeds. …"

An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity حسب Wang, Wei

"…Therapeutic agents labeled with reporters will interrogate tumor–drug interactions and permit analysis of biodistribution, pharmacokinetics and pharmacodynamics in real time. At the same time, we can apply the biologically effective dose for therapy, instead of the traditional maximum tolerated dose, to reduce systemic toxicity…"
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane حسب Vasavi, Boggarapu

"…The results indicated that tensile and flexural strength decreased by 35.16 % and 29.3 % respectively, from S1 to S10. …"
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Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer حسب Hehuan Zhu (4808445)

The role of objectively recorded smartphone usage and personality traits in sleep quality حسب Aftab Alam (5158601)

"…The usage data of smartphone apps were processed to calculate smartphone usage amounts and sleep variables, including sleep duration, sleep distraction, sleeping time, and wake-up time. The data were analyzed using the correlation coefficient and regression analyses.…"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …"

Bridging the gap between KG2 and grade one activity kit. (c2010) حسب Hammoud, Maya

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Removal of nitrate from JUST wastewater effluent: a case study حسب Al-Asheh, Sameer

"…From kinetic studies, equilibrium time was as short as 10 min. It was observed that pH plays an important role in the nitrate adsorption process. …"
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Thermodynamic analysis of a novel integrated geothermal based power generation-quadruple effect absorption cooling-hydrogen liquefaction system حسب Ratlamwala, Tahir Abdul Hussain

"…Moreover, increasing the temperature of geothermal source degrades the performance of the quadruple effect absorption system (QEAS), but at the same time it affects the liquefaction production rate of hydrogen gas in a positive way. …"
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. …"
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Expanding the donor pool حسب Ramos, Emilio

"…Based on Organ Procurement Transplant Network (OPTN) data as of January 11, 2002, the waiting time for a cadaveric renal transplant has grown to a mean of 422 d for patients with blood type AB and 1453 d for patients with blood type O. …"
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula حسب Luqman Atique (16036586)

"…The main objective of this paper is to analyze the long-term (1975–2023) trends of visibility fluctuations and development of haze for six countries including Kingdom of Saudi Arabia (KSA), Iraq (IRQ), Qatar (QTR), Kuwait (KWT), United Arab Emirates (UAE), and Oman (OMN). To comprehend the time-based patterns of visibility across the ME, we utilized the Mann Kendall (MK) and Modified Mann Kendall (MMK) trend estimators in both space and time. …"

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes حسب Goran Petrovski (129836)

"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …"

Do interleukin-6 and macrophage-migration inhibitory factor play a role during sex-associated susceptibility in murine cysticercosis? حسب Kabbani, Ahmad

"…However, in wild-type strains, females have twice as many parasites as males. At the same time, there is a decrease of 80% in testosterone and dihydrotestosterone serum levels, and a 100-fold increase in the levels of estradiol in infected male mice. …"
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