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561
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …”
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562
Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
Published 2023“…Moreover, it has been observed that, with the addition of nanoparticles to the working fluid, the thermal properties of the exchangers as well as the pressure drop increases while at the same time it reduces the boundary layer thickness. In addition, the Reynolds number affects the performance irrespective of the channel geometry. …”
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563
Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
Published 2022“…The primary outcome of the study was the change in the time spent in the target in range (TIR) of 70–180 mg/dl and HbA1c from baseline (MDI + CGM, 1 week) to study phase (AHCL, 12 weeks). …”
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564
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…This is in addition to the other effect represented by reducing the direct solar access to the building surfaces and decreases the solar energy gained by the buildings envelop through direct radiation. …”
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565
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566
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567
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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568
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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569
COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health
Published 2018“…Feasibility and acceptability findings indicated that the COPE program was a positive experience for teens. Significant decreases in depression and anxiety, and increases in QOL were also reported. …”
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570
Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050
Published 2024“…The disease burden of gout, LBP, and OA attributable to high BMI and gout attributable to kidney dysfunction increased, while the contribution of smoking to LBP and RA and occupational ergonomic factors to LBP decreased. Between 1990 and 2019, the slope index of inequality increased for six MSK disorders, and the relative concentration index increased for gout, NP, OA, and OMSKDs but decreased for LBP and RA. …”
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571
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
Published 2021“…However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019.…”
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572
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…</p><h3>Interpretation</h3><p dir="ltr">The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/hepatitis-b-vaccination" target="_blank">hepatitis B vaccination</a>. …”
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573
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
Published 2017“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
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574
Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles
Published 2021“…A D<sub>PSiMNPs</sub> = 100 mg/L was sufficient to achieve %η<sub>dem</sub> of 99.4% for C<sub>oil</sub> = 100 mg/L and slightly decreased to ~93% for C<sub>oil</sub> ~4000 mg/L. The PSiMNPs can be reused up to 15 times with a steady %η<sub>dem</sub> of 89.1% for C<sub>oil</sub> = 100 mg/L and 88.6% for C<sub>oil</sub> = 4000 mg/L. …”
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575
The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study
Published 2022“…This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East using data of Global Burden of Diseases (GBD) Study 2019.…”
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576
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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577
Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution
Published 2022“…Moreover, user preferences and network’s contextual information can differentiate between live and cached access patterns optimizing edge caching decisions. …”
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578
Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species
Published 2022“…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”
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579
Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
Published 2024“…In the common low-partner-number HSWNs, a significant proportion of NG incidence occurs among FSWs, with NG prevalence 13 times higher among FSWs than clients, and three times higher among clients than their spouses. …”
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580
Carbonate effects on hexavalent uranium removal from water by nanocrystalline titanium dioxide
Published 2006“…However, the capacity of the nanocrystalline titanium dioxide to remove U(VI) from water decreased in the presence of inorganic carbonate at pH > 6.0. …”
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