-
21
Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet
منشور في 2023"…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …"
-
22
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"
-
23
Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance
منشور في 2024"…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …"
-
24
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. Functional assays demonstrated an increase in lipid accumulation, bile acid synthesis and glycerol production, while a decrease in glucose uptake, glycogen storage, and Albumin secretion. …"
-
25
The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
منشور في 2023"…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …"
-
26
-
27
Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
منشور في 2021"…This study reports the time-dependent contextual and structural effects of TBI on hippocampal brain tissue. …"
-
28
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
منشور في 2025"…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …"
-
29
Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity
منشور في 2024"…In the ramp test, there was a significant decrease in muscle activation for rmsRF% (<i>P</i>= 0.049; d = 0.61) and rmsVM% (<i>P</i> = 0.01; d = 0.84) in peak power output (PPO). …"
-
30
Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
منشور في 2016"…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. The leading cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower respiratory infection for females. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
31
The Effect of Experimental Recuperative and Appetitive Post-lunch Nap Opportunities, With or Without Caffeine, on Mood and Reaction Time in Highly Trained Athletes
منشور في 2021"…<h3>Purpose</h3><p dir="ltr">To investigate the effects of placebo (PLA), 20 min nap opportunity (N20), 5mg·kg<sup>−1</sup> of caffeine (CAF), and their combination (CAF+N20) on sleepiness, mood and reaction-time after partial sleep deprivation (PSD; 04h30 of time in bed; <i>study 1</i>) or after normal sleep night (NSN; 08h30 of time in bed; <i>study 2</i>).…"
-
32
Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
منشور في 2020"…</p><h3>Results</h3><p dir="ltr">In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. This was driven by increased hexokinase-2 linked glucose metabolism and related increased MG formation. …"
-
33
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
منشور في 2024"…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
34
OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo...
منشور في 2023"…The couple's relationship quality also plays a significant role, with secure romantic attachment positively influencing prenatal attachment and promoting resilience in times of stress, while avoidant or anxious romantic attachment can lead to lower prenatal bonding and increased pregnancy-related worries.…"
-
35
A 28 nm CMOS 10 bit 100 MS/s Asynchronous SAR ADC with Low-Power Switching Procedure and Timing-Protection Scheme
منشور في 2021"…A single-side-fixed technique is utilized to reduce the number of capacitors; a parallel split capacitor array in combination with a partially thermometer coded technique can minimize the switching energy, improve speed, and decrease differential non-linearity (DNL). In addition, a compact timing-protection scheme is proposed to ensure the stability of the asynchronous SAR ADC. …"
-
36
World Cups apart: comparing <i> </i><i>New York Times</i> coverage of the 2018 Russia and 2022 Qatar World Cup tournaments
منشور في 2024"…This was reflected in the directionality of articles dealing with political issues surrounding the two tournaments, as well as reports dealing with fan experiences. While the New York Times’ negative directionality of the Russian World Cup decreased over time, coverage of the Qatar World Cup showed the opposite pattern, as negative directionality increased drastically post-event. …"
-
37
Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
منشور في 2022"…Future interventions at the personal, national and organizational levels are required to enhance the pharmacists’ wellbeing by decreasing stress, improving self-efficacy and resilience, and preventing burnout.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
38
Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study
منشور في 2015"…To highlight changes over time in RTI mortality among children and adolescents VRU and non-VRU globally, by region, and by country income level between 1990 and 2013. …"
-
39
Gut microbiome and Parkinson's disease: Perspective on pathogenesis and treatment
منشور في 2023"…Through the last two decades of research, there has been growing consensus that inflammation-mediated oxidative stress, mitochondrial dysfunction, and cytokine-induced toxicity are mainly involved in neuronal damage and loss associated with PD. …"
-
40
Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India?
منشور في 2025"…We conducted interrupted time series analyses by fitting a Poisson regression model. …"