PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes by Yehia M. Manawi (18091207)

“…The water flux of the fabricated membranes increased considerably (up to 20 times) along with the increase in CNT loading. Conversely, yield stress and Young’s modulus of the membranes dropped with the increase in the CNT loading mainly due to porosity increase. …”

DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations by El Maarri, Osman

“…Results DNA methylation changes were widespread on all autosomal chromosomes in 45,X and in 47,XXY individuals, with Turner individuals presenting five times more affected loci. Differentially methylated CpGs, in most cases, have intermediate methylation levels and tend to occur outside CpG islands, especially in individuals with Turner syndrome. …”
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Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis by Fateen Ata (12217764)

“…Female sex (61.5 % vs. 41.3 %, p = 0.019), hypoxemia (90 % vs. 59.2 %, p < 0.001), massive PE features (89.7 % vs. 30.1 %, p < 0.001), associated chronic kidney disease (CKD) (10.3 % vs. 1.4 %, p = 0.002), and the need for mechanical ventilation (28.2 % vs. 13.1 %, p = 0.02) were significantly associated with increased mortality. …”

Advanced direct air capture of CO₂ using air conditioning systems: a life cycle assessment by Namra Mir (17017734)

“…These reductions are attributed to decreased electricity requirements achieved via system synergies. …”

Seroprevalence of camel brucellosis in Qatar by Hashim Alhussain (9167136)

“…., < 4 years old) showed decreased seropositivity (3.4%, 95% CI, 0.1–17.8), compared to (22.8%, 95% CI, 17.4–29.0) seropositivity in camels ≥ 4 years of age, with a significant association between age groups and seropositivity (<i>P</i> = 0.02). …”

Experimental Investigation of FRP-Reinforced Concrete Columns Under Concentric and Eccentric Loading by Elmesalami, Nouran Zinelabdin Ahmed

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Microbial and operational factors affecting energy recovery potential for anaerobic membrane bioreactors treating different wastewater types by Ramadan, Lama

“…The third experiment treating poultry slaughterhouse wastewater (PSW) over three phases with decreasing hydraulic retention times (HRTs) concluded that the microbial adaptation to the high-strength wastewater can directly impact the energy produced from the system. …”
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3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations by Isra Marei (11312895)

“…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …”

Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review by Amani N. Alansari (19743643)

“…The findings underscore the urgent need for tailored assessment approaches, gender-responsive interventions, integrated school-based mental health services, and culturally focused prevention strategies that address both traditional and cyberbullying in the rapidly evolving sociocultural context of the AGC.…”

A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats by Firas Feki (17545638)

“…After enzyme treatment, simmondsin content decreased from 33.0 % to 3.0 % and glucose content increased from 16.2 % to 27.3 % reflecting simmondsin hydrolysis. …”

Nutritional Status and Clinical Outcomes of Children with Medical Complexity in the United Arab Emirates: A Retrospective Cross-Sectional Study by Al Slaybe, Maryam

“…Mixed feeding was linked to decreased WAZ (β= -0.465, p = 0.027) and WLZ (β = -1.329, p = 0.001) scores in comparison with exclusive breastfeeding, while formula feeding was associated with lower WLZ scores (β = -0.874, p = 0.025). …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Doua Abdelrahman (17280667)

“…Therefore, blood banks in Qatar might need to consider screening for B19V, especially when transfusion is intended for high-risk populations, including immunocompromised patients.…”

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study by Obaidullah Zafar (17910572)

“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …”

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice by Charlotte Rinne (18766966)

“…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …”

Biomarkers show promise for treatment of heart valve disease by Nature Research (16552612)

“…The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …”

Essays on international environmental policy by Marrouch, Walid

“…With the growing talk about the need to establish a new framework to deal with international environmental governance, it becomes relevant to shed some light on the interconnected landscape that characterizes environmental policy making. …”
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…These observations support the need to consider anti-NRP-1 as a potential targeted therapy for breast cancer patients who are identified with high NRP-1 levels. …”

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans by Kevin S. Chen (9201767)

“…Three of these compounds also decreased α-synuclein oligomers in mammalian neurons, including rifabutin which has not been previously investigated for Parkinson’s disease. …”