Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer حسب Hehuan Zhu (4808445)

"…We demonstrated an increase in immune cell density and a decrease in the distance of CD3⁺CD8⁺ T cells to the nearest tumor cell, in the immune active, ICR High, immune subtypes. …"

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…</p><h3>Results</h3><p dir="ltr">Our results showed for the first time that severe hypoxia can significantly impair Factor H secretion and CD59 expression in MSCs. …"

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes حسب Dina Abushanab (10696501)

"…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …"

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases حسب Hirbli, K.

"…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …"
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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals حسب Angy, Mallah

"…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …"
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Why do some countries produce more capital intensive output than others? حسب Toukan, Amjad

"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl حسب MOHAMED, SHAMSELDIN SAEED

"…On the demographic side, the massive external population migration that trickled towards the city resulted in a major defect in its demographic structure, which represented a decrease in the percentage of the citizen population to only about 10% of the non-citizen population. …"
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

"…The tracer Alk*, defined as the deviation of potential alkalinity (AP) (where AP = TA + 1.26 [NO3]) from conservative potential alkalinity ((ApC), (ApC = S Ap′S′ where A'P and S′ are mean values for the whole surface ocean) has values primarily determined by CaCO3 precipitation and dissolution. …"
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Differential water quality in confined and free-flowing water bodies, Lebanon حسب Korfali, Samira Ibrahim

"…Measured water parameters were temperature, pH, conductivity, BOD, HCO3-, Ca2+, Mg2+, Cl-, SO42-, PO43-, NO3-, NH3, Fe, Mn, Zn, Pb, and Cd. …"
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…This absence of caspase activation was confirmed by a 72 hours cytotoxicity assay on Panc-1 cells, which revealed the failure of the pan-caspase inhibitor, Z-VAD, to reverse or decrease arginine depletion-triggered cell death. These findings indicate that HuArgI (Co)-PEG5000-induced arginine depletion results in nonapoptotic, caspase-independent cell death. …"
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Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients حسب Bouquet, Antoine

"…Surgical resection of all tumor sites is the only treatment that enables prolonged survival, but the synchronous presentation of CLM has been associated with poor outcomes.1 Preoperative chemotherapy is widely used in these patients to provide early treatment of metastatic disease, to improve patient selection for surgical resection,2 and 3 and to decrease the recurrence rate after surgery.4 The traditional surgical strategy for patients with resectable synchronous CLM includes resection of the primary tumor followed by chemotherapy and then liver resection. …"
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …"

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis حسب Fateen Ata (12217764)

"…Patients with a 6-month DKA recurrence, female gender and T1DM had higher odds of 12-month recurrence, whereas a consult with a diabetes educator at the index admission was associated with decreased odds of recurrence.</p><h3>Conclusions/interpretation</h3><p dir="ltr">This is the most extensive study from the Middle-East region reporting on LOS, readmissions and the recurrence of DKA. …"

Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie حسب Echtay, Akram

"…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …"
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Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy حسب Moayyad Shawaqfah (17280637)

"…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …"

The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models حسب Al Toufaily, Sahar

"…All used doses of COE showed significant decrease in serum urea; however, a significant decrease in serum creatinine was observed only at 20 mg/kg COE. …"
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Prevalence and Potential Determinants of COVID-19 Vaccine Hesitancy and Resistance in Qatar: Results from a Nationally Representative Survey of Qatari Nationals and Migrants betwee... حسب Salma M. Khaled (16441981)

Inappropriate Medication Use in Elderly Lebanese Outpatients حسب Saab, Yolande B.

"…More than half (59.6%) of the patients taking drugs at the time of the study were taking at least one inappropriate medication. …"
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Online Monitoring of Outdoor Non-Ceramic Insulators حسب Shurrab, Ibrahim Yehia

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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…Conclusion Although most factors that affect the red cell transfusion rate for liver resection are patient- or tumor-related, the parenchymal transection technique is under the surgeon's control. The decrease in transfusion rate associated with the use of the 2-surgeon technique emphasizes the important role of the hepatobiliary surgeon in determining outcomes after liver resection. …"
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