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641
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…"
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642
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
منشور في 2023"…The additional increment enhanced the arrival time, dough development time, dough stability, the mixing tolerance index, and weakening. …"
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643
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644
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…</p><h3>Materials and methods</h3><p dir="ltr">We used RKO colon cancer cells, blocking HSP90 with the inhibitor AT13387 and HSP90 siRNA. …"
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645
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"
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646
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
منشور في 2022"…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…"
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647
A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats
منشور في 2009"…Secondly, using rats that received the same diets, real-time PCR was performed in the DVC, hypothalamus and nodose ganglia in order to compare TrkB receptor levels. …"
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article -
648
Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor
منشور في 2024"…The total carbon deposited was estimated to be around 18 g after 10,000 s of Time on Stream (TOS) at 650 °C. As the temperature increased, the total carbon deposition decreased, although this reduction became negligible beyond 850 °C. …"
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article -
649
A component analysis of positive behaviour support plans
منشور في 2012"…This paper investigates which components are most effective and which factors might mediate effectiveness. Method Sixty-one staff working with individuals with intellectual disability and challenging behaviours completed longitudinal competency-based training in PBS. …"
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article -
650
Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs
منشور في 2021"…<p dir="ltr">Purpose: This study aimed to assess the potential of flavonoids in combating CIPN. Methods: PubMed and Google Scholar were used, and studies that investigated flavonoids in models of CIPN and models of neuropathic pain similar to CIPN were included. …"
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651
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652
Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
منشور في 2022"…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …"
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653
Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
منشور في 2010"…Methods: A lentivirus was used to induce expression of the photoactivatable cationic channel channelrhodopsin-2 (ChR2) by RVLM Phox2b-containing neurons, a population that consists of central chemoreceptors (the ccRTN neurons) and blood pressure (BP)-regulating neurons (the C1 cells). …"
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article -
654
Associating learning technology to sustain the environment through green mobile applications
منشور في 2019"…Thus, it presents a stepping stone towards linking learning technology while at the same time sustaining the environment.…"
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article -
655
PSA-activated proaerolysin as a prostate specific cancer therapy
منشور في 2006"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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conferenceObject -
656
Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management
منشور في 2025"…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…"
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masterThesis -
657
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
658
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
منشور في 2011"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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article -
659
Removal of copper ions from aqueous solution using NaOH-treated rice husk
منشور في 2022"…The chemical treatment was carried out using NaOH solution and the effect of contact time (tc), adsorbent dosage (Dad), initial Cu (II) concentration ([Cu]i), and temperature (T) on the percentage removals of Cu (II) (%RCu) were investigated. …"
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660
Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes
منشور في 2018"…The water flux of the fabricated membranes increased considerably (up to 20 times) along with the increase in CNT loading. Conversely, yield stress and Young’s modulus of the membranes dropped with the increase in the CNT loading mainly due to porosity increase. …"