A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …”
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Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis... by Shajahan Joseph K (18472465)

“…<h3>Background</h3><p dir="ltr">Hamad General Hospital (HGH) is the main provider of Hemodialysis (HD) treatment in Qatar. …”

Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature by Henry C. Ezechukwu (13253406)

“…The results indicated that SARS-CoV-2 induces placenta inflammation, and placenta susceptibility to SARS-CoV-2 decreases across the pregnancy window. Thus, SARS-CoV-2 infection in early pregnancy may adversely affect the developing fetus.…”

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts by Mustafa T. Ardah (4858657)

“…<h3>Background</h3><p dir="ltr">Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy bodies. …”

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar by Shuja Mohd Reagu (12051406)

“…</p><h3>Results</h3><p dir="ltr">15.7% respondents report intent to not breastfeed. 21.4% respondents reported obsessive–compulsive symptoms. 77.3% respondents believed the biggest source of infection was from others while as only 12% of the respondents believed that the source of infection was through breastfeeding and 15.7% believed the vertical transmission as the main source of risk of transmission.</p><h3>Conclusions</h3><p dir="ltr">The rates of Obsessive–compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. …”

An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH₄-CO₂-H₂S by Hani Ababneh (9218272)

“…Overall, it was found that separation of CO₂ in solid phase improves when increasing the operating pressure up to 20 bar, and decreases at higher temperatures. Similarly, the separation of H₂S in either liquid or solid phase improves at higher pressures and lower temperatures. …”

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... by Ilham Bettahi (363910)

“…<h3>Background</h3><p dir="ltr">Skeletal muscle is the main site for insulin-dependent glucose disposal. …”

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…</p><h3>Aims</h3><p dir="ltr">Our main objective is to study the molecular mechanism of diabetes mellitus in LRBA-deficient patient and to investigate if LRBA has any role in insulin biosynthesis and secretion in β pancreatic cells.…”

Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis by Fateen Ata (12217764)

“…The presence of massive PE features is the main predictor of mortality in SPE patients. AC, TT, ST, and PT are all associated with decreased odds of death from SPE.…”

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…To capture time-series trends in CCF50 not explained by these covariates, we used a first-order autoregressive model on the residual term. …”
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Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Valery L Feigin (5320574)

“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. …”
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Preterm birth in low-middle income Countries by Alim, Swarray-Deen

“…Preterm birth (PTB), remains a major cause of significant morbidity and mortality world-wide with about 12–15million preterm births occurring every year. Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... by Robert C Reiner (5147636)

“…Interpretation By co-analysing geospatial trends in diarrhoeal burden and its key risk factors, we could assess candidate drivers of subnational death reduction. …”

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17 by Aniruddha Deshpande (4377094)

“…Interpretation Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. …”

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories.…”

The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort by Ken Van Alsenoy (14150559)

“…Compared to shoes only, mainly EVA tended to improve RE and comfort at submaximal running speeds. …”

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong Wang (47381)

“…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …”