Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complic... حسب Naila Rabbani (291722)

"…Downstream effector pathways of HK-linked unscheduled glycolysis are mitochondrial dysfunction and increased reactive oxygen species (ROS) formation; activation of hexosamine, protein kinase c, and dicarbonyl stress pathways; and increased Mlx/Mondo A signaling. …"

The Impact of Absenteeism and Islamic Work Ethics on Project Delivery in Public Projectized Organizations in the United Arab Emirates (UAE) حسب ALKEAIBI, NOORA RASHED

"…As the modern world demands a lot from the employees so the stress levels of the employees were increased and are not able to balance the work and the personal life where the individual is affected physically and psychologically that leads to employee’s absenteeism. …"
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Ecological impacts and potential hazards of nickel on soil microbes, plants, and human health حسب Muhammad, Rizwan

"…The contamination of agricultural soils with Ni, increases risks of its entry to terrestrial ecosystems and food production systems posing a threat to both food security and safety. …"
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The Candida albicans Dse1 Protein Is Essential and Plays a Role in Cell Wall Rigidity, Biofilm Formation, and Virulence حسب Khalaf, Roy A.

"…The heterozygote mutant exhibited increased susceptibility to calcofluor white, a cell wall disrupting agent, with a subsequent reduction in cell wall chitin content, decreased oxidative stress tolerance, a 30% reduction in biofilm formation, and a delay in adhesion that was mirrored by a reduction in virulence in a mouse model of infection. …"
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Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation حسب Malouf, Katia

"…It was observed that the mutant strain showed less oxidative stress tolerance and an increased susceptibility to calcofluor white, a cell surface disrupting agent that inhibits chitin fibre assembly which translated as a 40% decrease in cell wall chitin content. …"
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Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes حسب Eman Hussen (18877108)

"…Previous studies have revealed changes in gene expression patterns, disruptions in cellular signaling pathways, and increased oxidative stress resulting from e-cigarette exposure. …"

Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation حسب Feng, Samuel

"…Oxidative stress (OS) has been shown to have a negative effect on the autonomic nervous system (ANS) and on ANS modulation of heart rate. …"
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Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes حسب Naila Rabbani (291722)

"…<div><p>The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin resistance and vascular complications in diabetes. Consequently, the increased flux of glucose metabolism without a change in the expression and activity of glycolytic enzymes produces a wave of increased glycolytic intermediates driving mitochondrial dysfunction and increased reactive oxygen species (ROS) formation, the activation of hexosamine and protein kinase C pathways, the increased formation of methylglyoxal-producing dicarbonyl stress, and the activation of the unfolded protein response. …"

Applications, advancements, and challenges of cyanobacteria-based biofertilizers for sustainable agro and ecosystems in arid climates حسب Shazia Bibi (16500318)

"…<p>Based on the increasing world population, the food demands have tremendously increased. …"

Unveiling final-year students and new graduates’ concerns, preparedness, and learning experiences during the pandemic in Qatar: A cross-sectional survey حسب Yasin M. Yasin (14779381)

"…While 61 % of new graduates felt well-prepared in their nursing skills, and 87 % felt confident, less than half of the students still in their final year of education felt prepared or confident. Increased stress and a perceived impact on education quality were reported due to changes in learning modalities. …"

Using GIS and optimization to manage construction and demolition waste: The case of abandoned quarries in Lebanon حسب AlZaghrini, Nadine

"…Increased stress on raw material and limited landfill space due to increasing rates of urbanization have encouraged efforts to divert Construction and Demolition Waste (C&DW) away from landfills toward sorting, recycling, and reusing. …"
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Glucose excursions in type 2 diabetes modulate amyloid-related proteins associated with dementia حسب Abu Saleh Md Moin (6189512)

"…Dementia is a recognized complication of type 2 diabetes (T2D) with an increasing prevalence, and AD is the most common cause. …"

Enhancement of polysulfone ultrafiltration membrane with third generation poly(amido amine)-graphene oxide nanocomposite حسب Ahmed T. Yasir (16518552)

"…The abundance of -OH and -NH2 groups on the synthesized nanocomposites resulted in improved hydrophilicity of the membrane and aided improving the membrane porosity and increased its pore radius. As a result, the membrane pure water permeation flux increased by 1300 % for the new membrane compared to pristine PSF membrane to reach a maximum of 124.5 LMH/bar while maintaining a high BSA rejection rate of 99 % with a flux recovery rate of 55 %. …"

Sustainable Production of Nannochloris atomus Biomass Towards Biodiesel Production حسب Touria Bounnit (16936899)

"…Similarly, the lipid content was strongly influenced by the elevation of temperature; indeed, it increased up to ~3 folds when the temperature increased from 20 to 40 °C. …"

The role of dietary antioxidants in type 2 diabetes and neurodegenerative disorders: An assessment of the benefit profile حسب Munazza Tamkeen Fatima (17316955)

"…ROS is also associated with increased mitochondrial dysfunction and neuroinflammation, aggravating neurodegenerative conditions in the body, particularly with age. …"

Bond durability performance of sand-coated BFRP bars in high-strength fiber reinforced concrete حسب Abathar Al-Hamrani (16494884)

"…<p dir="ltr">The ever-increasing utilization of fiber-reinforced polymer (FRP) bars has led to a surge in research regarding their bonding properties with concrete. …"

Numerical Evaluation of Pre-Damaged Beam Using Recycled Concrete Aggregate Strengthened by FRP Sheets حسب MOHAMMED, MOHAMMED ASHRAF MOUSTAFA

"…Fiber reinforced polymer (FRP) has been increasingly used nowadays as an effective rehabilitation method in buildings due to structural flaws and aging of building structures, therefore it is an effective method to repair beams, columns, slabs. …"
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An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School حسب AL AHMAD, ALAAEDDIN MEHY

"…However, those Arabic-speaking students attending non-Arabic schools become less proficient in the Arabic language and continually fall behind their peers in Arabic schools. This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. …"
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Oxandrolone Treatment in Adults with Severe Thermal Injury حسب Btaiche, Imad F.

"…Muscle protein catabolism in patients with severe thermal injury is the result of stress-induced increased release of cytokines and counterregulatory hormones. …"
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Ecological impacts and potential hazards of nickel on soil microbes, plants, and human health حسب Muhammad Rizwan (536386)

"…The contamination of agricultural soils with Ni, increases risks of its entry to terrestrial ecosystems and food production systems posing a threat to both food security and safety. …"