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321
Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort
Published 2024“…Elevated QTc was observed in CAD patients, whereas decreased QTc was correlated with decreased levels of calcium and potassium. …”
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322
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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323
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Published 2011“…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …”
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324
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…”
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325
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …”
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326
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”
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327
Novel proteins implicated in lipid metabolism disorders
Published 2016“…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …”
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328
Acute pain management and assessment
Published 2012“…Furthermore, as pain severity scores increased, the adequacy of pain management decreased. Only 22% of the patients had a daily follow-up, and the majority of those continued to receive inappropriate therapy. …”
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329
Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach
Published 2018“…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…”
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330
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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331
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
Published 2021“…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1<sup>KD</sup>) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …”
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332
Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
Published 2020“…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …”
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333
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334
The Development of Metal-Free Porous Organic Polymers for Sustainable Carbon Dioxide Photoreduction
Published 2024“…The use of porous organic polymers (POPs) for CO₂ fixation and capture and sequestration to produce beneficial compounds to reduce global warming is still receiving a lot of interest. Visible light-responsive organic photopolymers that are functionally designed and include a large number of heteroatoms and an extended π-conjugation allow for the generation of photogenerated charge carriers, improved absorption of visible light, increased charge separation, and decreased charge recombination during photocatalysis. …”
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335
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…The present pilot study represents a novel dietary means by which to reduce BCAA, and as such, provides a blueprint for a potential dietary therapeutic in obesity/diabetes.…”
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336
Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images
Published 2022“…Early diagnosis is the only way to increase the treatment options which then decreases the death rate and increases the chance of survival in patients. …”
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337
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study...
Published 2021“…</p><h3>Results </h3><p dir="ltr">The means (SD) of age and BMI of class III obesity subjects was 32.32 (8.36) years and 49.02 (6.28) kg/m<sup>2</sup>, respectively. …”
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338
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…”
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339
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”
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340
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …”