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a large » _ large (Expand Search)
large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b largest » _ largest (Expand Search)
i levels » _ levels (Expand Search), 1 levels (Expand Search), 6 levels (Expand Search)
b large » _ large (Expand Search), i large (Expand Search), _ larger (Expand Search)
a large » _ large (Expand Search)
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Decreased MBP levels in the brain in <i>Large</i><sup><i>myd/myd</i></sup> mice.
Published 2020“…<p><b>A,</b> Brain sections of eight-week-old control and <i>Large</i><sup><i>myd/myd</i></sup> mice at the level of the corpus callosum were obtained for immunostaining for MBP (Scale bars: 200 μm). …”
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Spatial information of excitatory neurons in APP/PS1 mice are decreased in dCA1 and vCA1.
Published 2024Subjects: -
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Differential expression analysis of nuclear transcripts after siAPOBEC3A depletion reveals induction of TP53 targets and decreases in cell cycle and cell growth regulator transcrip...
Published 2024“…Data were analyzed by Fisher’s exact test, **** <i>p</i> ≤ 0.0001. (B) siAPOBEC3A treatment increases <i>CDKN1A</i> nuclear transcript levels in MCF10A cells by RNA-seq. …”
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Longer polyQ sequences decrease the nuclear localization of AR in the absence of hormone.
Published 2022Subjects: -
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Deletion of murine <i>Rhoh</i> leads to de-repression of <i>Bcl-6</i> via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma
Published 2022“…The loss of Rhoh in Bcl-6<sup>Tg</sup> mice led to a more rapid disease progression. Mechanistically, we demonstrated that deletion of Rhoh in these murine lymphoma cells was associated with decreased levels of the RhoH binding partner KAISO, a dual-specific Zinc finger transcription factor, de-repression of KAISO target Bcl-6, and downregulation of the BCL-6 target Blimp-1. …”
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Foldases and holdases each decrease the level of unfolded protein.
Published 2020“…The benefit of a large spare foldase capacity can be seen from the rapid rise of the unfolded level [<i>U</i>], up 4-fold for only a 2-fold increase in unfolding load (thin black lines). …”