Expression of lipid biosynthetic genes is decreased with polyamine depletion. by Yazmin E. Cruz-Pulido (20285238)

Group-level narrow- and broad-band spectral changes after hemispherotomy reveal a marked EEG slowing of the isolated cortex, robust across patients. by Michele Angelo Colombo (22446342)

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

Narrow- and broad-band spectral changes after hemispherotomy in an awake representative patient, displaying marked electroencephalography (EEG) slowing of the isolated cortex. by Michele Angelo Colombo (22446342)

(A) Auxiliary marking points to ensure complete and accurate seating of the prosthesis. by Long Li (6555)

Skin marks is the S1 Fig title. by Mercedes Soto-González (20422078)

ROC analysis to mark selectivity results in mostly mixed-selective units. by Thomas S. Wierda (22404198)

“…The large number of mixed selective units also results in a significant decrease in accuracy when these neurons are targeted as compared to <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013559#pcbi.1013559.g006" target="_blank">Fig 6c</a> where there was no significant effect visible after targeting mixed selective units, likely because there were less mixed selective units present. …”

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Map of Pakistan with marked Punjab province. by Sumaira Sumaira (21453523)

<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> by Dmitri Samovski (305400)

“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”

PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

Tornado diagram showing the results of a one-way sensitivity analysis conducted for the scenario with vaccination. by Albertus Constantijn Sloof (20405090)

<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b> by Denise M. Drotar (21679539)

“…Insulin-positive (INS+) single cells (≤10µm), cell clusters (>10 to <35µm), small- and medium-sized islets (35-100µm and 100-200µm) were significantly lost at type 1 diabetes onset, while large INS+ islets (>200µm) were preserved. Moreover, changes in endocrine composition also occurred in mAAb+ donors, including a significant decrease in the INS+ islet fraction. …”

Tornado diagram showing the results of a one-way sensitivity analysis conducted for the scenario without vaccination. by Albertus Constantijn Sloof (20405090)

General procedure for the synthesis of B. by Xueqin lu (22250795)

miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b> by Bettina Mittendorfer (88840)

“…<a href="" target="_blank"> Total postprandial glucose appearance rate was lower after compared with before weight loss in both the BDT and RYGB groups because of a decrease in endogenous glucose production, without a difference between groups. …”