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marked increased » marked increase (Expand Search), marked increases (Expand Search), marked decrease (Expand Search)
large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b marked » _ marked (Expand Search), a marked (Expand Search), _ market (Expand Search)
n marked » _ marked (Expand Search), a marked (Expand Search), _ market (Expand Search)
i large » _ large (Expand Search), a large (Expand Search), via large (Expand Search)
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Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia.
Published 2022“…(<b>D)</b> Mann–Whitney test, <i>N</i> (WT) = 142 cells from 2 mice, <i>N</i> (KO) = 83 cells from 1 mouse. ****: <i>p</i> < 0.0001. …”
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<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b>
Published 2025“…<p dir="ltr">We used a dual (intravenous and oral) glucose tracer protocol to evaluate rates of glucose appearance into the circulation, insulin-mediated glucose disposal (IMGD), and non-insulin-mediated glucose disposal (NIMGD) for four hours after consumption of a mixed meal in people with obesity and type 2 diabetes before and after marked (~20%) weight loss, induced by behavioral diet therapy (BDT, n=11) or Roux-en-Y gastric bypass (RYGB) surgery (n=9).…”
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<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b>
Published 2025“…We hypothesized that alterations in adipose tissue biology and adipose tissue-related factors in plasma are involved in mediating the systemic metabolic benefits of weight loss.</p><p dir="ltr"><b>Research Design and Methods</b>: We evaluated blood and adipose tissue samples obtained from ten adults with obesity and type 2 diabetes before and after marked (16%-20%) weight loss and >50% increase in whole-body insulin sensitivity, assessed by using the hyperinsulinemic-euglycemic clamp procedure.…”
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