Chronic colitis induces marked changes in protein expression in the adult heart and blood. by Yanbo Tang (11457519)

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Withdrawal of Type I JAKinibs increased STAT phosphorylation, a phenomenon present but markedly lower in Type II JAKinibs. by Ilya Gurevic (1326786)

PD-1 deficiency does obviously not change B cell and CD11b⁺ myeloid cell IHC staining in livers following <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

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3D interactions between the ligand and the protein_DNA complex in the first (C1) and second (C2) clusters. by Ahmed A. Gaber (13302308)

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Region-specific gain and loss of repressive marks in aged somatic tissues. by Cheng-Lin Li (3620321)

De-repression of gene expression and responsive histone marks. by Dana Lau-Corona (8861900)

“…(<b>C</b>) Shown at the right are 8 different combinations of histone mark changes, one of which was assigned to each E1/E2-KO-responsive gene based on whether there was a decrease in H3K27me3 marks at either the gene body or promoter region, and/or an induction of H3K27ac marks or of H3K4me1 marks, as determined by GREAT analysis (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008796#sec012" target="_blank">Methods</a>). …”

Regulatory T cells are not obviously induced during early phase of <i>S</i>. <i>japonicum</i> infection in C57BL/6 WT mice. by Liaoxun Lu (179293)

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Increase of T cell presence in the liver of PD-1-deficient mice infected with <i>S</i>. <i>japonicum</i> for 8 weeks. by Liaoxun Lu (179293)

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S1 File - by Hongyu Li (1332669)

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Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening by Emily K. Sims (5278130)

“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…<p><b>(A)</b> NKCC1 mRNA expression levels in newborn and adult microglia isolated from C57BL/6J mice compared to neural progenitors derived from E17 embryonic hippocampi. …”

Group-level narrow- and broad-band spectral changes after hemispherotomy reveal a marked EEG slowing of the isolated cortex, robust across patients. by Michele Angelo Colombo (22446342)

“…This decrease was larger in the disconnected than in the contralateral cortex. …”

Pericentric heterochromatin structural integrity is disrupted in the absence of CFDP1 due to loss of core heterochromatin protein, HP1α and H3K9me3 marks. by Gokul Gopinathan (7930679)

HSV-1 increases <i>de novo</i> lipogenesis. by Camilla Albano (16446679)

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Foxp3 expression in wildtype mice with 8 weeks of <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

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PD-1-deficient T cells dramatically outcompete wildtype T cells <i>in vivo</i> in the absence of natural Tregs during chronic <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

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PD-1 deficiency does not significantly impact the pathogen load and pathology following <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

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