Chronic colitis induces marked changes in protein expression in the adult heart and blood. by Yanbo Tang (11457519)

Region-specific gain and loss of repressive marks in aged somatic tissues. by Cheng-Lin Li (3620321)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Expression of lipid biosynthetic genes is decreased with polyamine depletion. by Yazmin E. Cruz-Pulido (20285238)

PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

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Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…(<b>C)</b> NKCC1 mRNA levels in isolated NKCC1 KO microglia was markedly reduced in comparison to WT cells. …”

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

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Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

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miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

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miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

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Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening by Emily K. Sims (5278130)

“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

Pericentric heterochromatin structural integrity is disrupted in the absence of CFDP1 due to loss of core heterochromatin protein, HP1α and H3K9me3 marks. by Gokul Gopinathan (7930679)

The activation of MARK2 is correlated with the phosphorylation of eIF2α, and the signaling pathway is independent of the previously known kinases. by Yu-Ning Lu (10291271)

“…<p>(<b>A</b>) Deletion of the MARK2 gene decreases the phosphorylation of eIF2α-⁵¹S in human HAP1 cells. …”

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Nemp1 KO mice display increased splenic stress erythropoiesis. by Didier Hodzic (132944)

Simplified scheme illustrating the inhibitory effect of nNOS on the PPP during the initiation of GSIS. by Ingmar Lundquist (46422)

“…<p>1) A marked increase in glucose concentration results in a large accumulation of the released insulin at the exocytotic sites of nNOS-associated insulin granules (denoted as orange circles on insulin granules) in the PPP. …”

HSV-1 increases <i>de novo</i> lipogenesis. by Camilla Albano (16446679)

CMS121 and C75 reduce the infectivity of HSV-1 viral particles. by Camilla Albano (16446679)

Impact of CMS121 and C75 on HSV-1 entry into Vero cells. by Camilla Albano (16446679)