Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening by Emily K. Sims (5278130)

“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”

Chronic colitis induces marked changes in protein expression in the adult heart and blood. by Yanbo Tang (11457519)

The level of miRNA 221 in the myocardium of MIRI mice was decreased. by Hongyu Li (1332669)

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Treatment with 10μM benidipine decreases N8-3C3 NKT hybridoma cell activation and IL-2 production. by Andrés F. Londoño (6857828)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Region-specific gain and loss of repressive marks in aged somatic tissues. by Cheng-Lin Li (3620321)

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

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Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

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miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

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PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

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miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

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Lamin-B protein marks the onset of physiological decline in young adult male <i>Drosophila</i>. by Wei-Qi Lin (2518108)

Decreasing trends in HbA1c are visible when using the average HbA1c for each dataset for T1Ds, but not T2Ds. by Hans F. Dias (14486401)

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

Plasma cholesterol and LDL-C levels. by Xueqin lu (22250795)

The activation of MARK2 is correlated with the phosphorylation of eIF2α, and the signaling pathway is independent of the previously known kinases. by Yu-Ning Lu (10291271)

“…<p>(<b>A</b>) Deletion of the MARK2 gene decreases the phosphorylation of eIF2α-⁵¹S in human HAP1 cells. …”

Deletion of Ssp2 or/and Gsk3/Gsk31 markedly suppressed CLZ, TER or CoCl₂-induced Sre1 activity. by Hao Miao (1742044)

“…<p>The Δ<i>ssp2</i>, Δ<i>gsk3</i>Δ<i>gsk31</i>, Δ<i>ssp2</i>Δ<i>gsk3</i>, Δ<i>ssp2</i>Δ<i>gsk31</i> or Δ<i>ssp2</i>Δ<i>gsk3</i>Δ<i>gsk31</i> cells showed a significant decrease in Sre1 activity and delay in the peak rising of the SRE2 reporter stimulated with 8 μg/ml CLZ (A)_, 8 μg/ml TER (B) or 0.32 mM CoCl₂ (C). …”

CMS121 and C75 reduce the infectivity of HSV-1 viral particles. by Camilla Albano (16446679)

Impact of CMS121 and C75 on HSV-1 entry into Vero cells. by Camilla Albano (16446679)

Average of % peptides counts for different classes of proteins at different germination time points and significant p-value indicated as compared to soaked sample (*p< 0.05, **p<0.... by Indrani Bera (804948)