Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

Subjects:

Chronic colitis induces marked changes in protein expression in the adult heart and blood. by Yanbo Tang (11457519)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Region-specific gain and loss of repressive marks in aged somatic tissues. by Cheng-Lin Li (3620321)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…(<b>C)</b> NKCC1 mRNA levels in isolated NKCC1 KO microglia was markedly reduced in comparison to WT cells. (<b>D, E)</b> NKCC1 protein expression in a large number of randomly sampled NKCC1 KO microglia cells is markedly reduced compared to WT cells. …”

Pericentric heterochromatin structural integrity is disrupted in the absence of CFDP1 due to loss of core heterochromatin protein, HP1α and H3K9me3 marks. by Gokul Gopinathan (7930679)

HSV-1 increases <i>de novo</i> lipogenesis. by Camilla Albano (16446679)

Subjects:

Nemp1 KO mice display increased splenic stress erythropoiesis. by Didier Hodzic (132944)

Supplementary Material for: Marked choroidal thinning observed after intravitreal brolucizumab injection by Ueta Y. (14066457)

Simplified scheme illustrating the inhibitory effect of nNOS on the PPP during the initiation of GSIS. by Ingmar Lundquist (46422)

“…<p>1) A marked increase in glucose concentration results in a large accumulation of the released insulin at the exocytotic sites of nNOS-associated insulin granules (denoted as orange circles on insulin granules) in the PPP. …”

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”

Nectin-1 staining increases in keratinocytes surrounding HSV1 foci, but decreases within the foci. by Hafsa Rana (8201886)

Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening by Emily K. Sims (5278130)

“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”

Increase of T cell presence in the liver of PD-1-deficient mice infected with <i>S</i>. <i>japonicum</i> for 8 weeks. by Liaoxun Lu (179293)

Subjects:

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

S1 File - by Ingmar Lundquist (46422)

“…Culturing at high glucose increased both nNOS and iNOS activities inducing a marked decrease in GSIS in a following short-term incubation at high glucose. …”