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341
The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study
منشور في 2022"…This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East using data of Global Burden of Diseases (GBD) Study 2019.…"
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342
Dietary protein level alters gentamicin-induced nephrotoxicity in rats
منشور في 2007"…Aminoglycosides (AG) such as gentamicin are antimicrobial drugs widely used in the hospital setting due to their efficacy in the treatment of severe gram-negative bacterial infections. …"
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343
Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
منشور في 2009"…Conversely, ABCG2 expression studied on brain capillaries from MPTP-treated mice was decreased (1.3-fold, p<0.05) and ABCB1 expression increased (1.43-fold, p<0.05) as an off-setting of brain transport. …"
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344
A New Extension of Generalized Exponential Distribution with Application to Ozone Data
منشور في 2017"…The distribution is capable of monotonically increasing, decreasing, bathtub and upside down shaped hazard rates. …"
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345
The DJ-1 superfamily members YhbO and YajL from Escherichia coli repair proteins from glycation by methylglyoxal and glyoxal
منشور في 2016"…Both proteins are involved in protection against environmental stresses. Here, we show that, like DJ-1 and Hsp31, they repair glyoxal- and methylglyoxal-glycated proteins. …"
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346
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
منشور في 2023"…The objective of this exercise was to understand the phenomenon of saltwater intrusion using an existing set of data analyzed with the convective–diffusion equation and the two-region mobile–immobile solution model. …"
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347
Optical coherence tomography findings in autoimmune retinopathy
منشور في 2012"…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …"
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348
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…In summary, EMT-associated overexpression of PD-L1 was partially independent of promoter CpG methylation and more likely to be dependent on posttranslational histone modifications. …"
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349
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"
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350
Reduction of laboratory utilization in the intensive care unit
منشور في 2016"…We hypothesized that a program that involves physician and staff education and alters the current ICU order sets will lead to a sustained decrease in routine laboratory test ordering. …"
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351
Basin of Attraction through Invariant Curves and Dominant Functions
منشور في 2015"…We study a second-order difference equation of the form z<inf>n+1</inf> = z<inf>n</inf> F (z<inf>n-1</inf>) + h, where both F (z) and z F (z) are decreasing. We consider a set of invariant curves at h = 1 and use it to characterize the behaviour of solutions when h > 1 and when 0 < h < 1. …"
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352
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
منشور في 2024"…Incidence data were extracted from insurance claims and inpatient discharge sources and analysed with disease modelling meta-regression, version 2.1 (DisMod-MR 2.1). Years of life lost (YLLs) were estimated by combining death counts with standard life expectancy at the age of death. …"
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353
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
منشور في 2023"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
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354
Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
منشور في 2020"…We consider dicarbonyl stress, the functional vulnerability of the plant proteome to arginine-directed glycation and the likely role of methylglyoxal-mediated glycation in the activation of the unfolded protein response in plants. …"
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355
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
منشور في 2022"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
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356
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
منشور في 2022"…However, its effective utilization is hindered by the adverse side effects associated with its administration, the detriment to the patients’ quality of life, and general toxicity to healthy fast-dividing cells. …"
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357
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
منشور في 2023"…The spectral information obtained for the photochemical reaction of DCF in a set of neat solvents demonstrates that the photoconversion reaction rate of DCF is not only medium polarity dependent but also hydrogen-bonding dependent. …"
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358
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
منشور في 2022"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
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359
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
منشور في 2022"…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …"
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360
Mortality and associated risk factors of COVID-19 infection in dialysis patients in Qatar: A nationwide cohort study
منشور في 2023"…The mean length of hospital stay was 19.2 ± -12 days. Mortality due to COVID-19 among our dialysis cohort was 15%. …"