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381
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
منشور في 2024"…Herein we assessed the effect of high glucose concentration and related increased cellular MG on activation status of IRE1α, PERK and ATF6. Human aortal endothelial cells and HMEC-1 microvascular endothelial cells were incubated in low and high glucose concentration to model blood glucose control, with increase or decrease of MG by silencing or increasing expression of glyoxalase 1 (Glo1), which metabolizes MG. …"
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382
Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
منشور في 2024"…The proposed work has the following contributions and merits: (i) The paradigms of evolutionary computation, reinforcement learning, and Markov chain are incorporated into an integrational framework for feature selection in high dimensional spaces in a recursive manner. …"
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383
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
منشور في 2024"…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"
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384
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385
Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
منشور في 2010"…In-hospital transfusions are still reported in one third of patients in major series. Data on factors affecting blood transfusions in large series of liver resection are limited. …"
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article -
386
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387
Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
منشور في 2021"…The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …"
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388
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
منشور في 2008"…Six eyes underwent fluorescein angiography at the 12-week follow-up visit; 3 (50%) of these eyes had decreased leakage compared with baseline. Both stabilization of vision and improved CMT were maintained for at least 8 weeks after a single injection in almost all eyes. …"
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article -
389
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
390
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391
Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development
منشور في 2021"…IRF6 targeted sequencing revealed mutations in two distinct families; one of the two mutations (p.Ala2Valfs*53), has not been reported in the literature previously. …"
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masterThesis -
392
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393
CEAP
منشور في 2016"…To reduce the overhead of the proposed detection model and make it feasible for the resource-constrained nodes, we reduce the size of the training dataset by (1) restricting the data collection, storage, and analysis to concern only a set of specialized nodes (i.e., Multi-Point Relays) that are responsible for forwarding packets on behalf of their clusters; and (2) migrating only few tuples (i.e., support vectors) from one detection iteration to another. …"
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article -
394
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395
Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System
منشور في 2021"…<p dir="ltr">Diabetic sensorimotor polyneuropathy (DSPN) is an early indicator for non-healing diabetic wounds and diabetic foot ulcers, which account for one of the most common complications of diabetes, leading to increased healthcare cost, decreased quality of life, infections, amputations, and death. …"
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396
Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
منشور في 2025"…In ACG patients, the pooled effect showed a percentage of IOP reduction (IOPR%) of 35.22% with a mean IOP reduction of −9.51 mmHg, <i>p</i>< 0.001 at 12 months, and an IOPR% of 27.47% with a mean reduction of −6.37 mmHg, <i>p</i> < 0.001 at 24 months. …"
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397
A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
منشور في 2022"…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…"
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398
DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
منشور في 2019"…Here, we assessed the effect of DNAJB3 on the respective activity of JNK1 and IKKβ in cell-based assays. Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …"
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399
Modeling the risk-based decisions of the microgrid in day-ahead energy and reserve markets considering stochastic dispatching of electrical and thermal energy storages
منشور في 2022"…However, the proposed robust two-stage stochastic model leads to a smaller reduction of the MGO’s first-stage decisions in the worst case in comparison with the conventional methods, i.e. deterministic and probabilistic ones. This issue proves the effectiveness of the proposed approach to protect the MGO’s decisions against the uncertainties.…"
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400
Outcome of home parenteral nutrition in 251 children over a 14-y period
منشور في 2016"…Results: A total of 251 patients were included: 217 (86%) had a PDD. The mean ± SD age at HPN onset was 0.7 ± 0.3 y, with a mean duration of 1.9 ± 0.4 y. …"
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