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AKT inhibition decreases neuroblast populations.
Published 2012“…Otic vesicles were isolated from HH18 chicken embryos, made quiescent and cultured for 20 h in serum-free culture medium without additions (0S, a) or in the presence of IGF-I (10 nM, b), LY294002 (LY, 25 µM, c) or AKTi VIII (AKTi, 50 µM, d). …”
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GSK343 decreased tumor stemness.
Published 2021“…Treatment with GSK343 significantly decreased tumorsphere formation by both the COA3 (A) and COA6 (B) cells, representing a decrease in stem cell-like phenotype. …”
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GluN2A(D731N) decreases channel open probability.
Published 2017“…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”
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OP50 <i>E. coli</i>-fed nematodes are generally healthy while pathogen-fed worms demonstrate a decrease in overall health.
Published 2014“…(B) The average pumping rate for nematodes fed <i>P. aeruginosa</i> is decreased when compared to N2 animals fed OP50. Worms with a <i>pmk-1(km25)</i> background exhibit the largest decrease in pumping rate. …”
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Decreased cell stiffness after dissociation of intercellular adhesion.
Published 2014“…The corresponding cross section height measurements show a height decrease by slightly less than 100 nm (from ∼10 nm to −100 nm in the encircled area; lower panel); the arrow in the AFM images points to an intact intercellular connection before cutting (<b>E1</b>) and the disappearance thereof after cutting (<b>E2</b>). …”
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Decreased oscillatory flow decreases <i>klf2a</i> expression.
Published 2009“…<p>(A) RFF is decreased by alterations in heart rate. …”
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Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…<b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …”
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Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG.
Published 2013“…Arrow in (E) indicates a BrdU/NeuN double-labeled cell in the DG of a 9 month-old mouse. …”
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Clinical characteristics of patients in the increased-, stable-, and decreased-RPR groups.
Published 2023Subjects: