Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity حسب Imran Ramzan (15430807)

"…The BCAA-restricted diet marginally lowered Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) levels: baseline 1.5 ± 0.2 to 1.0 ± 0.1; (p = 0.096).</p> <p>Conclusion: We successfully lowered circulating BCAAs by 50% while maintaining iso-nitrogenous, iso-caloric dietary intakes, and while meeting the recommended daily allowances (RDA) for protein requirements. …"

Electrically conductive hybrid organic crystals as flexible optical waveguides حسب Li, Liang

"…The elements respond rapidly to temperature by curling or uncurling in about 0.2 s, which in one typical case corresponds to exceedingly fast deformation and recovery rates of 2187.5° and 1458.3° , respectively. In cyclic operation mode, their conductivity decreases less than 1% after 10,000 thermal cycles. …"
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Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)

"…We also compared these trends to those of smoked tobacco over the same time period. …"

The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 حسب Arash Etemadi (330880)

"…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …"

An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health حسب Belqes Alsadi (18695031)

"…Lower sodium levels were found in diabetics, potentially stemming from clinical factors including specific medications, hormonal imbalances, unmanaged diabetes. We believe Dapagliflozin prescriptions in Qatar were associated with decreased Gamma Glutamyltransferase and Aspartate Aminotransferase enzyme levels, confirming prior research. …"

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Brittney S Sheena (9715568)

"…By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. …"

The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …"

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy حسب Abu Saleh Md Moin (6189512)

"…<h2>Introduction</h2> <p>We sought to determine whether chromogranin A-positive hormone-negative (CPHN) endocrine cells are increased in the pancreas of pregnant women, offering potential evidence in support of neogenesis.…"

Expanding the donor pool حسب Ramos, Emilio

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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salam Salloum-Asfar (656363)

"…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …"

Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media حسب Kashif Rasool (2542492)

"…We investigated in detail the inhibition mechanism of SRBs by CS@LS in seawater media. …"

Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation حسب Bartholomew, Aaron

"…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …"
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Clinical characteristics and treatment outcomes of coats disease in a Saudi Arabian population حسب Al-Qahtani, Abdullah

"…Results: The most common presenting complaint was decreased visual acuity followed by strabismus and then leukocoria. …"
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The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort حسب Ken Van Alsenoy (14150559)

"…Albeit not reaching statistical significance (P = 0.11, η² = 0.12), RE on average improved in EVA (+2.1±4.8% and +2.9±4.9%) and TPU (+0.9±5.9% and +0.9±5.3%) compared to CON at LS and HS, respectively. …"

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Health Services Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12913-022-08981-5" target="_blank">https://dx.doi.org/10.1186/s12913-022-08981-5</a></p>…"

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 حسب Hmwe Hmwe Kyu (8674014)

"…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …"

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar حسب Dina Abushanab (10696501)

"…<h3>Background</h3><p dir="ltr">There is a lack of evidence regarding the economic impact of antimicrobial stewardship program (ASP).We sought to evaluate the cost-benefit of the mature ASP use compared to premature ASP use in the adults’ general medicine settings in Qatar. …"

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study حسب Rupert Bourne (603842)

"…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …"

α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain حسب Eid, Fady

"…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…"
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