Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

The apparent Ca²⁺ affinity of release is decreased by hydrophobic mutations. by Matthew R. Bowers (8423115)

“…The significant rightward shift in the curve (EC50, non overlapping confidence intervals) indicates a decrease in the apparent Ca²⁺ affinity of neurotransmitter release.…”

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Dose response of airways to Methacholine shows a decreased contractility in <i>GSTCD</i>^-/- mouse lungs following LPS treatment. by Bo Liu (127343)

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. by Ashley L. Comer (8299128)

The decreasing rates of V_p with temperature. by Nazlı Tunar Özcan (14833635)

“…The V_p and the σ_t of Çankırı rock salt decrease with increasing temperatures of samples whereas the σ_c increases. …”

FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma. by Laura L. Stafman (6577184)

“…There was a trend toward decreased Ki67 staining in FTY720-treated tumors (p = 0.29). …”

No change in muscle size and force, but a decrease in TB mass in 1-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

LOH resulting in 189R/R produces a strong decrease in drug susceptibility. by Pétra Vande Zande (17628246)

Datasheet1_Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c.pdf by Benjamin Morat (17677977)

“…No significant difference was observed between medians of HbA1c_mean and HbA1c_after values (8.37% [7.88; 9.32%] vs. 8.50% [7.70; 9.50%], respectively; p = 0.391). …”

Datasheet2_Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c.pdf by Benjamin Morat (17677977)

“…No significant difference was observed between medians of HbA1c_mean and HbA1c_after values (8.37% [7.88; 9.32%] vs. 8.50% [7.70; 9.50%], respectively; p = 0.391). …”

Oral administration of TVSE decreases angiogenesis in 4T1 tumors in BALB/c mice. by Hyun Sook Lee (8039876)

(a) Mycelial diameter (mm) determination on PDA plates, (b) Inhibition diameters, and (c) inhibition percentages of <i>Aspergillus flavus</i> treated with <i>U. epigea</i> extract... by Martha Cebile Jobe (21175426)

Growth on stiff substrate results in mild lifespan extension but a decrease in organismal health. by Maria Oorloff (19658113)

Vascular and parenchymal inflammation are key components of cerebral malaria in <i>P</i>. <i>berghei</i> ANKA-infected mice and are decreased in α_D ^-/- mice. by Isaclaudia G. de Azevedo-Quintanilha (8173734)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”