COVID-19 and Anemia: What Do We Know So Far? by Luai Abu-Ismail (10712857)

LDL-C Targets in Secondary Prevention: How Low Should We Go? by Karim Bayoumy (3496688)

“…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …”

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the affected signaling networks were TGFβ1, SPP1, and ERK regulatory networks. Conclusions. We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.…”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…PP2A, GSK3β and Tau reside together in a complex, which facilitates their interaction and (dys)-function as has been reported for several neurological disorders. In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. …”

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study by Houssein H., Ayoub

“…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …”
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>) by Albandari Bin-Ammar (16381128)

“…Fish (n = 300, initial body weight = 10.02 g ± 0.11 g) received supplementary CURNPs at rates of 0 (control; CURNPs0), 50 (CURNPs50), 100 (CURNPs100) and 150 (CURNPs150) mg/kg diet for 90 days. …”

Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles by Wamda Faisal Elmobarak (17058024)

“…A D_PSiMNPs = 100 mg/L was sufficient to achieve %η_dem of 99.4% for C_oil = 100 mg/L and slightly decreased to ~93% for C_oil ~4000 mg/L. …”

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model by Haissam Abou-Saleh (497840)

“…Our data highlight the absence of both acute and teratogenic toxic effects of ChNPs (~100% survival rate) even at the higher concentration employed (200 mg/L). …”

Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles by Muneer M. Ba-Abbad (14151660)

“…<p dir="ltr">In this study, the nanoparticles (NPs) of ZnO and Co²⁺ ions doped ZnO (doped ZnO) were incorporated into a matrix of polysulfone (PSf) membranes to enhance their surface properties prepared using a simple wet phase inversion technique. The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. …”

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics by Farah F. Salameh (21797300)

“…Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …”

Rapid mercury removal using living indigenous microalgal communities for water treatment applications by Amr Nasr Fekry (22521185)

“…The maximum biosorption capacity reached 0.10 mg/g at 100 μg/L initial concentration. Notably, <i>MIMA</i> maintained both viability and removal efficiency when exposed to Hg for 3 days without any addition of nutrients suggesting resilience under nutrient-limited conditions. …”

Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO₂ intercooled and reheated cycles under design and off‐d... by Wahib A. Al‐Ammari (18877408)

“…At optimized conditions (<i>P</i>_c,o = 30 MPa, Pc,o = 8 MPa, TIT = 744°C, CIT = 30°C [wet‐cooling]), the ICC shows superior energetic performance (52.08%) compared to 47.97% for DRC, 49.20% for PIC, and 48.62% for RHC. …”

An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing by Mohammadjafar Hadad (17541345)

“…The results indicate that the MQL technique increases the grinding performance of Inconel 738 by reducing ground workpiece surface roughness and decreasing the coolant–lubricant consumption comparing to the conventional wet grinding process. …”