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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in...
Published 2015“…This need for translation is related to the language used to study sciences in high schools. …”
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The Effect of DJ-1 on Invasion and Invadopodia Formation in Glioblastoma Multiforme
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Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic
Published 2024“…These vehicles boost confidence, increase road capacity, and decrease traffic accident. The major benefit is a decrease in traffic enforcement, plus self-driving cars consume less fuel than other types of vehicles and don't require auto insurance. …”
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Cell surface proteome characterization of the Candida albicans DSE1 mutant. (c2011)
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…Furthermore, confocal microscopy analysis of BODIPY-stained untreated, steatotic, and Ex-4-treated steatotic cells showed that Ex-4 significantly decreases the number of lipid droplets. Fatty acid uptake and transport genes were also affected by MALAT1 knockdown. …”
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The Impacts of COVID-19 on the Well-Being of students with SEN in Primary Stage in Dubai Schools
Published 2022“…The current paper aimed to verify the impact of the Covid-19 pandemic on the well-being of a sample of (74) students who were classified by teachers as a student with Special Educational Needs in five of Dubai primary schools. The study methodology depended on the descriptive-analytical approach, the researcher prepared a well-being questionnaire for students with special educational needs SEN, and its validity and reliability were verified. …”
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
Published 2023“…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…The upregulation of Voltage-dependent anion-selective channel protein 1 (1.9-fold), Major vault protein (1.8-fold), Bax (1.16-fold), and Cytochrome C (1.39-fold) indicate the activation of the intrinsic pathway. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of -0.16 mmol/L and -0.48 mmol/L, respectively. …”
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis
Published 2020“…Quality assessment was done using the ROBINS-I and Cochrane tools for risk of bias and analyses were performed using RevMan version 5.1.…”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”
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The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …”