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we decrease » a decrease (Expand Search), nn decrease (Expand Search), mean decrease (Expand Search)
wt decrease » a decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
_ decrease » _ decreased (Expand Search)
5 wt » _ wt (Expand Search), 5 ht (Expand Search), i wt (Expand Search)
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Significant decrease of SMAD4 protein in DBA iPSCs.
Published 2015“…<p>DBA iPSCs (labelled as “<i>RPS19/RPL5</i> mutant” or “<i>RPS19/RPL5</i> mutant-”), the corrected DBA cells (expressing a WT version of the mutated gene, <i>RPL5</i> or <i>RPS19</i>, labelled as “<i>RPS19/RPL5</i> mutant <i>RPS19/RPL5</i>” or “corrected <i>RPS19/RPL5</i> mutant”) and the control GFP cells (expressing GFP, labelled as “<i>RPS19/RPL5</i> mutant GFP”) were cultured and the nuclear and cytoplasmic protein was extracted from iPSCs for western blot analysis, and RNA for q-PCR analysis. …”
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Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs.
Published 2015“…The ratio of protein level to WT is labelled under the image. A) No change of mRNA level of <i>SMAD2</i> or <i>SMAD3</i> in the DBA iPSCs with <i>RPS19</i> or <i>RPL5</i> mutations. …”
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Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice
Published 2017“…The survival rate was significantly higher (81.1% vs. 48.2%, <i>P</i><0.05), and the cardiac rupture rate was significantly lower in AIM<sup><b>‒/‒</b></sup> mice than in WT mice (10.8% vs. 31.5%, <i>P</i><0.05). The number of M1 macrophages and the expression levels of M1 markers (iNOS and IL-6) in the infarcted myocardium were significantly lower in AIM<sup><b>‒/‒</b></sup> mice than in WT mice. …”
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