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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019Subjects: -
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AKT inhibition decreases neuroblast populations.
Published 2012“…SOX2 is expressed in the otic epithelial neuroblast population (a, arrowhead) and it is significantly increased in presence of IGF-I (b, arrowhead, e) but it is markedly reduced in the presence of either AKTi or LY (c and d, arrowheads, e). …”
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At lower concentrations, METH decreases LTP.
Published 2010“…At 0.1 µM METH, LTP was 1.58±.08 [<i>n</i> = 13(5)] (Fig. 1B); at 1 µM METH, LTP was 1.50±.07 [<i>n</i> = 13(7)] (Fig. 1C); at 10 µM METH, LTP was 1.58±.07 [<i>n</i> = 14(8)] (Fig. 1D); at 30 µM METH, LTP was 1.37±.06 [<i>n</i> = 15(4)] (Fig. 1E); and at 60 µM METH, LTP was 1.32±.24 [<i>n</i> = 4(2)] (Fig. 1E). …”