Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …"

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function حسب Julien Bricambert (19738237)

"…The HDAC activity reduction was associated with decreased <i>HDAC5</i> / <i>Hdac5</i> and <i>HDAC6</i> / <i>Hdac6</i> expression in human and mice adipocyte fraction. …"

Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties حسب Slimani, Ahmed

"…The lead-free Na 0.5 Bi 0.5 0.94 Ba 0.06 TiO 3 (NBT-6BT) ceramics was fabricated at various sintering temperatures using a conventional solid-state reaction method. …"
احصل على النص الكامل

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

"…We report the impact of dysprosium (Dy, with y = 0.01, 0.02, 0.05 and 0.08) substitution in (Na0.5 Bi0.5)0.94 Ba0.06TiO3 (NBT-6BT) lead-free ceramics. The structural, vibrational dielectric, ferroelectric and electrocaloric (EC) properties of all samples were systematically investigated. …"
احصل على النص الكامل

Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor حسب Ebrahimi, Parisa

"…As the temperature increased, the total carbon deposition decreased, although this reduction became negligible beyond 850 °C. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor حسب Ahmed Aheed Ali Mohammed (22155979)

"…As the temperature increased, the total carbon deposition decreased, although this reduction became negligible beyond 850 °C. …"

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…The rate of HAP-attributable DALYs was higher for males (1530·5, 1023·4–2263·6) than for females (1318·5, 866·1–1977·2). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... حسب Thozhukat Sathyapalan (704787)

"…</p><h3>Conclusions</h3><p dir="ltr">This post-hoc analysis revealed that 12 weeks of atorvastatin treatment significantly decreased the markers of adipose tissue dysfunction and inflammation, namely ASP, IL-6 and MCP-1 in obese women with PCOS. …"

OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... حسب Pia Tohme Khalaf (17425551)

Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA حسب Muhammad Shehab (16904880)

Evapotranspiration and water availability response to climate change in the Middle East and North Africa حسب Salah Basem Ajjur (14150967)

"…This study, then, implements Penman and Budyko approaches to climatic data retrieved from the sixth phase of the Coupled Model Intercomparison Project (CMIP6) to assess evapotranspiration and water availability evolutions through the twenty-first century. …"

The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention حسب Almonzer Al-Qiami (22393303)

"…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …"

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review حسب Maged S. Alhammadi (14150757)

"…PubMed, Scopus, Science Direct, Web of Science, Cochrane, and LILACS were searched up to October 2021. …"

Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Kinetic studies showed superior correlation with the pseudo-second-order model (R² > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"

Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review حسب Hamid El Bilali (15864930)

"…Utilizing a rigourous methodology, we screened 236 articles from the Web of Science database as of March 2023, narrowing the corpus to 62 significant publications that meet comprehensive eligibility criteria. …"

Social Network Analysis for Precise Friend Suggestion for Twitter by Associating Multiple Networks Using ML حسب Dharmendra Kumar Singh Singh (19517710)

"…This approach is by and large used to decrease the dimensionality of the information alongside its feature space. …"