Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability حسب Bárbara Arévalo (4053358)

"…Chemical structures of selective blockers of TASK channels contain aromatic groups and amide bonds. Using this rationale, we designed and synthesized a series of compounds based on 3-benzamidobenzoic acid. …"

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis حسب Chenlu Zhang (508309)

"…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …"

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis حسب Chenlu Zhang (508309)

"…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …"

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity حسب Xiao-Meng Liu (778197)

"…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …"

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity حسب Xiao-Meng Liu (778197)

"…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …"

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity حسب Xiao-Meng Liu (778197)

"…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …"

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity حسب Xiao-Meng Liu (778197)

"…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …"

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity حسب Xiao-Meng Liu (778197)

"…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …"

<i>Aspergillus flavus</i> mRNA expression (a) <i>aflD</i> and (c) <i>aflR</i> and phylogenetic analysis of (b) <i>aflD</i> and (d) <i>aflR</i> after exposure to 50 mg/mL of <i>U. e... حسب Martha Cebile Jobe (21175426)

Inhibition of PKCδ causes a decrease in viral replication. حسب Brian D. Carey (6092747)

Titanate Nanosheets/Cellulose Composite Showing Improved Crystallinity and Decreased Water Wettability by Gamma-Irradiation حسب Yaowaluk Tariwong (22630109)

EQI decreases malonyl-CoA levels in <i>S</i>. <i>aureus</i>. حسب Erica C. Larson (1344687)

C4BP is necessary and sufficient for serum-mediated decrease in neutrophil internalization of OpaD+ Gc. حسب Lacie M. Werner (14710419)

C-indexes for the nomograms. حسب Na Li (6550)

"…The primary endpoint was considered as OS and CSS. We conducted trend analysis of the incidence, OS and CSS rates of liver metastases in ovarian cancer. …"

The decreasing rates of V_p with temperature. حسب Nazlı Tunar Özcan (14833635)

"…The V_p and the σ_t of Çankırı rock salt decrease with increasing temperatures of samples whereas the σ_c increases. …"

Molluscicidal activity and physiological toxicity of quaternary benzo[c]phenanthridine alkaloids (QBAs) from <i>Macleaya cordata</i> fruits on <i>Oncomelania hupensis</i> حسب Wenshan Ke (7490798)

"…We extracted quaternary benzo[c]phenanthridine alkaloids (QBAs) from <i>Macleaya cordata</i> fruits. …"

Germ cell size decreases before corpse formation. حسب Tea Kohlbrenner (19476160)

How the variation in inhibitor concentration throughout one day affects the value of IC₅₀/(IC₅₀ + [R]) for different Abl1 inhibitors. حسب J. Roadnight Sheehan (20141887)

Supplemental Material for MSG L-00273-2023R1;Hemopexin Reverses Activation of Lung eIF2a and Decreases Mitochondrial Injury in Chlorine Exposed Mice حسب Sadis Matalon (13571353)

Fitting curve of rock E₅₀. حسب Junxia Zhou (14381598)