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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Published 2025“…FindingsIn 2021, 2·67 billion (95% uncertainty interval [UI] 2·63–2·71) people, 33·8% (95% UI 33·2–34·3) of the global population, were exposed to HAP from all sources at a mean concentration of 84·2 μg/m3. Although these figures show a notable reduction in the percentage of the global population exposed in 1990 (56·7%, 56·4–57·1), in absolute terms, there has been only a decline of 0·35 billion (10%) from the 3·02 billion people exposed to HAP in 1990. …”
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Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
Published 2017“…Diabetic rats were injected intraperitoneally with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. …”
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Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
Published 2016“…Diabetic rats were injected intraperitonially with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Blood samples were collected for assessment of liver toxicity and colon tumor incidence and size were studied histologically. HC showed a dose-dependent decrease in cell survival with an IC50 of 18 and 14.5 μg/ml after 24 and 48 h respectively. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Methods HaCaT-ras II-4 epidermal squamous cells were treated with HC (1, 5, 10, 25 and 50 μg/ml), and cell viability was evaluated with WST 1 assay kit. …”
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
Published 2018“…Treatment with HC25, HC5%Top or Cisplatin showed a significant decrease in papilloma yield and volume. …”
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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines
Published 2022“…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …”
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Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …”
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Supplementation of retrobulbar block with clonidine in vitreoretinal surgery
Published 2011“…The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…This research addresses critical knowledge gaps regarding living microalgae-mediated mercury removal and demonstrates <i>MIMA's</i> potential as a sustainable, efficient solution for mercury contamination in aquatic ecosystems, maintaining viability even under nutrient-limited conditions while effectively reducing mercury concentrations to near guideline values at the lowest initial level (10 μg/L).…”